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Simultaneous Determination of Benzodiazepines and Ketamine from Alcoholic and Nonalcoholic Beverages by GC-MS in Drug Facilitated Crimes

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An Erratum to this article was published on 06 November 2009

Abstract

A GC-MS method with HP-5MS capillary column was developed for the simultaneous determination of underivatized flunitrazepam, clonazepam, alprazolam, diazepam and ketamine from drinks by extraction with chloroform: isopropanol 1:1 (v/v). All linearity ranges were between 50 and 1,000 μg mL−1 for all compounds both in beer and in peach juice. Limit of detection was between 1.3 and 34.2 μg mL−1, limit of quantification was between 3.9 and 103.8 μg mL−1, the range of recoveries was 73.0 and 112.6% for all drugs in both beverages. The reported method was sensitive, rapid, and suitable for the analysis of the spiked drinks as evidence of sexual assault and robbery phenomena.

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Acknowledgments

This research was supported by the Research Fund of the University of Istanbul. Project number: UDP-378/26082004. We wish to thank the Chairman of the Council of Forensic Medicine in Turkey, Dr. Keramettin Kurt.

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Authors and Affiliations

  1. Institute of Forensic Sciences, Istanbul University, 34303, Istanbul, Turkey

    Munevver Acikkol, Selda Mercan & Sukriye Karadayi

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  1. Munevver Acikkol
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  2. Selda Mercan
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  3. Sukriye Karadayi
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Correspondence to Munevver Acikkol.

Additional information

An erratum to this article can be found at http://dx.doi.org/10.1365/s10337-009-1396-1

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Acikkol, M., Mercan, S. & Karadayi, S. Simultaneous Determination of Benzodiazepines and Ketamine from Alcoholic and Nonalcoholic Beverages by GC-MS in Drug Facilitated Crimes. Chroma 70, 1295–1298 (2009). https://doi.org/10.1365/s10337-009-1278-6

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