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LC Determination of Phthalate Esters in Water Samples Using Continuous-Flow Microextraction

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Abstract

A novel method, continuous-flow microextraction (CFME) combined with liquid chromatography (LC) with variable-wavelength detector (VWD), has been developed for the determination of three phthalate esters (dimethyl phthalate (DMP), diethyl phthalate (DEP), and di-n-butyl phthalate (DnBP)) in water samples. Experimental parameters including extraction solvent, solvent drop volume, flow rate of sample solution, extraction time and ionic strength, which affected the extraction efficiency, were studied and optimized. Under the optimum extraction conditions, the method yields a linear calibration curve in the concentration range of 10–10,000 ng mL−1 for target analytes. The enrichment factors of this method for DMP, DEP and DnBP reached at 27, 44 and 20, respectively, and the detection limits were 2, 1 and 5 ng mL−1, respectively. Good repeatability of extraction was obtained with relative standard deviations below 8.6%. The results demonstrated that CFME followed by LC-VWD is a simple and reliable technique for the determination of phthalate esters in water samples.

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Acknowledgments

Financial support from National Nature Science Foundation of China (Grant No. 20705010) is gratefully acknowledged.

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Authors and Affiliations

  1. Key Laboratory of Pesticide and Chemical Biology of Ministry of Education, College of Chemistry, Central China Normal University, 430079, Wuhan, People’s Republic of China

    Pei Liang, Qian Li, Jing Xu & Dan Du

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  1. Pei Liang
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  2. Qian Li
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  3. Jing Xu
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  4. Dan Du
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Correspondence to Pei Liang.

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Liang, P., Li, Q., Xu, J. et al. LC Determination of Phthalate Esters in Water Samples Using Continuous-Flow Microextraction. Chroma 68, 393–397 (2008). https://doi.org/10.1365/s10337-008-0744-x

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