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Extraction of Quinolizidine Alkaloids in Non Aqueous Basic Conditions: The Case of Spartium junceum Flowers

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Abstract

In this work the use of basic nonaqueous conditions is suggested as a general method for the extraction of quinolizidine alkaloids. The extraction of quinolizidine alkaloids from fresh flowers of Spartium junceum is performed in ethanolic basic conditions. The procedure is efficient and selective. The extract is essentially formed by N-formylcytisine, N-methylcytisine, cytisine and anagyrine. The method allows a high recovery of N-formylcytisine which becomes the predominant alkaloid in S. Junceum flowers.

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Authors and Affiliations

  1. Dipartimento di Scienze Farmaceutiche, Università della Calabria, Via P. Bucci, Cubo 15/C, 87030, Arcavacata di Rende (CS), Italy

    Emilia L. Belsito, Maria L. Di Gioia, Antonella Leggio, Angelo Liguori, Francesca Perri & Carlo Siciliano

  2. Dipartimento di Chimica, Università della Calabria, Via P. Bucci, Cubo 15/D, 87030, Arcavacata di Rende (CS), Italy

    Giuseppe Chidichimo

Authors
  1. Emilia L. Belsito
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  2. Giuseppe Chidichimo
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  3. Maria L. Di Gioia
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  4. Antonella Leggio
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  5. Angelo Liguori
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  6. Francesca Perri
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  7. Carlo Siciliano
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Correspondence to Angelo Liguori.

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Belsito, E.L., Chidichimo, G., Di Gioia, M.L. et al. Extraction of Quinolizidine Alkaloids in Non Aqueous Basic Conditions: The Case of Spartium junceum Flowers. Chroma 68, 345–349 (2008). https://doi.org/10.1365/s10337-008-0706-3

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  • DOI: https://doi.org/10.1365/s10337-008-0706-3

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