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UPLC-PDAD Analysis for Simultaneous Determination of Ten Synthetic Preservatives in Foodstuff

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Abstract

A novel and quick ultra performance liquid chromatography-photo diode array detector method has been developed and validated for the simultaneous determination of ten synthetic preservatives in foodstuff. An Acquity BEH C18 column (50 × 2.1 mm i.d., 1.7 μm particle size) was used. The mobile phase consisted of a mixture of acetonitrile and 20 mM potassium dihydrogen phosphate/phosphoric acid (pH 4.29) buffer at the gradient elution program. The ten compounds behaved linearly in the 0.100–20.0 μg mL−1 concentration range, with correlation coefficient >0.999. The precision inter- and intra-day of the ten synthetic preservatives at three concentration levels were 0.11–5.75% (RSD). The recoveries at three different concentrations were 88.7–99.0%, with coefficients of variation <6.3%. The method was applied to the determination of preservatives in cola beverages, fruit-flavoured carbonate beverages and fruit juice beverages, and proved its suitability for quick and reliable quality control.

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Authors and Affiliations

  1. Food Safety Department, Chinese Academy of Inspection and Quarantine, Beijing, 100025, People’s Republic of China

    Li Xiu-Qin, Yong Wei, Ling Yun, Yang Min-Li & Chu Xiao-Gang

  2. College of Food Science and Technology, Jiang Nan University, Wuxi, 214036, People’s Republic of China

    Ji Chao

Authors
  1. Li Xiu-Qin
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  2. Ji Chao
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  3. Yong Wei
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  4. Ling Yun
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  5. Yang Min-Li
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  6. Chu Xiao-Gang
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Correspondence to Chu Xiao-Gang.

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Xiu-Qin, L., Chao, J., Wei, Y. et al. UPLC-PDAD Analysis for Simultaneous Determination of Ten Synthetic Preservatives in Foodstuff. Chroma 68, 57–63 (2008). https://doi.org/10.1365/s10337-008-0645-z

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  • DOI: https://doi.org/10.1365/s10337-008-0645-z

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