Skip to main content
SpringerLink
Log in

Separation of the Geometric Isomers of 4-Octyl-1,1a,2,3,4,5,6,6a-Octahydro-Cyclopropa[f]Indene-1-Carboxylic Acid Ethyl Ester and their Positional Isomers by Reversed-Phase HPLC

  • Published:
Chromatographia Aims and scope Submit manuscript

Abstract

A high-performance liquid chromatography (HPLC) method for the separation of geometric and positional isomers is described. A gas chromatography-mass spectrometry (GC-MS) method for the detection and evaluation of various isomers is described. The developed method was able to separate the isomers in the purity range of 97.96% to 99.3% (GC analysis).

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  • Zhou XC, Wu CY, Ran Lu X, Chen YY (1994) J Chromatogr A 662:203–218

    Article  CAS  Google Scholar 

  • Kawaguchi Y, Tanaka M, Nakae M, Funazo K, Shono T (1983) Anal Chem 55:1852–1857

    Article  CAS  Google Scholar 

  • Harino H, Kimura HHK, Tanaka M, Shono T (1990) J Chromatogr A 522:107–116

    Article  CAS  Google Scholar 

  • Knox H, Kaur B, Millward GR (1986) J Chromatogr A 352:3–25

    Article  CAS  Google Scholar 

  • Knox H, Kritz J, Adamcova E (1988) J Chromatogr A 447:13–27

    Article  CAS  Google Scholar 

  • Wan QH, Shaw PN, Davies MC, Barrett DA (1995) J Chromatogr A 697:219–227

    Article  CAS  Google Scholar 

  • Wan QH, Shaw PN, Davies MC, Barrett DA (1996) Anal Chem 68:437–446

    Article  CAS  Google Scholar 

  • Weber TP, Carr PW (1990) Anal Chem 62:2620–2625

    Article  CAS  Google Scholar 

  • Snyder LR (1968) Principles of Adsorption Chromatography, Marcel Dekker, New York

  • Truedsson LA, Smith BEF (1981) J Chromatogr 214:291–306

    Article  CAS  Google Scholar 

  • Berger TA (1995) In: Packard Column SFC, Royal Society of Chemistry, Cambridge

  • Terabe S, Otsuka K, Ichikawa K, Tsuchiya A, Ando T (1984) Anal Chem 56:111–113

    Article  CAS  Google Scholar 

  • Hussain Z (2003) Design and Synthesis of New Liquid Crystalline Materials, Ph.D. Dissertation, Technical University of Braunschweig, Germany

  • Luhowy R, Keehn PM (1977) J. Am. Chem. Soc. 99:3797–3805

    Google Scholar 

  • Zindel J, Maitra S, Lightner DA (1996) Synthesis 1217–1222

Download references

Author information

Authors and Affiliations

  1. Max-Planck-Institut für Bioanorganische Chemie, Postfach 101365, 45470, Mülheim an der Ruhr, Germany

    Z. Hussain

Authors
  1. Z. Hussain
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Z. Hussain.

Additional information

Revised: 16 November 2005 and 9 March 2006

Rights and permissions

Reprints and permissions

About this article

Cite this article

Hussain, Z. Separation of the Geometric Isomers of 4-Octyl-1,1a,2,3,4,5,6,6a-Octahydro-Cyclopropa[f]Indene-1-Carboxylic Acid Ethyl Ester and their Positional Isomers by Reversed-Phase HPLC. Chroma 63, 327–330 (2006). https://doi.org/10.1365/s10337-006-0776-z

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1365/s10337-006-0776-z

Keywords

Search

Navigation