Abstract
Two efficient methods for the determination of 1,1-dichloro-1-fluoroethane (Freon F-141b) in formulated polyol and rigid polyurethane foam by dynamic-headspace-gas chromatography-ion trap-mass spectrometry were developed and validated. Rigid polyurethane foam was efficiently dissolved in dimethylformamide by heating at the temperature of 60 °C for 2 h.Validation was carried out in terms of limits of detection (LOD), limits of quantitation (LOQ), linearity, precision and recovery. LOD values of 4.00 μg kg−1 for rigid polyurethane foam and 0.73 μg kg−1 for formulated polyol were achieved, whereas linearity was statistically verified over one order of magnitude. Precision was evaluated testing two concentration levels. Good results were obtained both in terms of intra-day repeatability and between-day precision: RSD % lower than 4% (n = 6) at the concentration of 15 μg kg−1 were calculated for intra-day repeatability. Extraction recoveries up to 92.6±1.6 % (n = 3) were also calculated by the addition of Freon F-141b to the samples analysed. Both the methods were applied for the analysis of a number of formulated polyol and rigid polyurethane foam samples.
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References
Kintz P, Baccino E, Tracqui A, Mangin P (1996) Forensic Sci Int 82:171–175
Cooper KM, Chang SF (1995) J Chromatogr B 667:85–93
Sibley HW (1997) In: Kirk-Othmer encyclopedia of chemical technology, 4th edn, Vol. 21, Howe-Grant M. (ed) John Wiley & Sons, Inc., New York.
Rowland FS (1991) Environ Sci Technol 25:622–628
Kurylo MJ (1990) Proceedings of ASHRAE 1989 CFC technology conference at the national institute of standard and technology, Gaithersburg, Md., Sept. 27–28 1989, ASHHRAE Publications Department, Atlanta, Ga.:5–15
Lacis A (1981) Geophys Res Lett 8:1035–1037
The 1987 Montreal protocol on substances that deplete the ozone layer, United Nations Environment Programme, September 1987
Smart BE, Fernandez RE (1997) In: Kirk-Othmer Encyclopedia of chemical technology, 4th edn, Vol. 11, Howe-Grant M (ed) John Wiley & Sons, Inc., New York
Commission Regulation No. 2037/2000. Official J Eur Communities, L 244, 29/9/2000
Bayer O (1947) Angew Chem A59:257–262
Ulrich H (1997) In: Kirk-Othmer Encyclopedia of Chemical Technology, 4th edn, vol. 24, Howe-Grant M (ed) John Wiley & Sons, Inc., New York,
Saunders JH, Frisch KC (1962) In: Polyurethanes: chemistry and technology, part 1 and 2, vol. 16, John Wiley & Sons, Inc., New York
US Environmental Protection Agency, Environmental Monitoring and Support Laboratory (1986) The determination of halogenated chemicals in water by the P&T method, method 502.1, Cincinnati, OH, USA
The Fitness for Purpose of Analytical Methods: A Laboratory Guide to Method Validation and Related Topics, EURACHEM Guide, 1st English Edition 1.0-1998, LGC (Teddington) Ltd., http://www.eurachem.ul.pt/
Draper N, Smith H (1981) In: Applied regression analysis, John Wiley & Sons, New York
Massart DL, Vandenginste BGM, Buydens LMC, De Jong S, Lewi PJ, Smeyers-Verbeke J (1997) In: Handbook of chemometrics and qualimetrics: Part A, Data handling in science and technology, Vol. 20A, Vandenginste BGM and Rutan SC (eds), Elsevier, Amsterdam
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Antolini, B., Bianchi, F., Bottazzi, M. et al. Development and Validation of Novel DH-GC-ITMS Methods for the Determination of Freon F-141b in Formulated Polyol and Rigid Polyurethane Foam. Chromatographia 60, 323–327 (2004). https://doi.org/10.1365/s10337-004-0393-7
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DOI: https://doi.org/10.1365/s10337-004-0393-7