Synthesis of Some Allyl-β-Cyclodextrin Derivatives and their Properties as Capillary GC Stationary Phases

Summary

Three β-Cyclodextrin derivatives (β-CDs) were synthesized by substituting the 2,6-OH groups of β-CD with allyl groups and the 3-OH groups with three different acyl groups (valeryl, heptanonyl, octanoyl). The chromatographic properties of these β-CDs as stationary phases for capillary gas chromatography (CGC) were studied. The test results showed that the three β-CDs possessed good coating properties and that the capillary columns coated with them exhibited high column efficiency. These β-CDs can separate not only the disubstituted benzene isomers but also some racemic compounds.