Determination of Antioxidants and Preservatives in Cosmetics by SPME Combined with GC–MS
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A rapid and simple procedure for the determination of antioxidants and preservatives in cosmetics has been developed utilizing solid-phase microextraction combined with GC–MS. A silica fiber coated with polyacrylate provided the highest extraction efficiency. Detection limits in the range from 0.4 to 8.5 ng mL−1 were obtained. Linearity is over a wide range from 1 to 2,000 ng mL−1 with a relative standard deviation under 16%. Cosmetic from a local supermarket were analysed for antioxidants and preservatives to demonstrate the effectiveness of the proposed method. The concentration of antioxidants and preservatives determined was 20–1,218 μg g−1 for methylparaben and 5–3,779 μg g−1 for propylparaben.