Abstract
The routine method for preparation of silica core-shell nanoparticles (NPs) is to carry out nucleation and shell coating through the hydrolysis of silane in water in oil (W/O) microemulsion to form three-dimensional netted silica shell. We found that electrostatic interaction of the core materials with shell materials would determine whether the stable core-shell silica NPs formed or not. The traditional important factors such as molecular weight of core materials or the thickness of the shell have no obvious relationship with it. And the stability of the core-shell silica NPs can be improved after changing the electric charge polarity by regulating the experiment condition of relevant materials if some core materials cannot be doped inside to form the stable core-shell silica NPs based on the traditional method, which provided experimental and theoretic foundation for preparation and application of the core-shell silica NPs.
Similar content being viewed by others
References
Yang, H. H., Zhang, S. Q., Chen, X. L. et al., Magnetite containing spherical silica NPs for biocatalysis and bioseparations, Anal. Chem., 2004, 76(5): 1316–132.
Morey, T. E., Varshney, M., Flint, J. A. et al., Activity of microemulsion-based NPs at the human bio-nano interface: Concentration-dependent effects on thrombosis and hemolysis in whole blood, J. Nanoparticles Res., 2004, 6: 159–170.
Cui, Z., Mumper, R. J., Plasmid DNA-entrapped NPs engineered from microemulsion precursors: in vitro and in vivo evaluation, Bioconjug. Chem., 2002, 13(6): 1319–1327.
He, X. X., Wang, K. M., Tan, W. H. et al., Bioconjugated NPs for DNA protection from cleavage, J. Am. Chem. Soc, 2003, 125: 7168–7169.
He, X. X., Wang, K. M., Tan, W. H. et al., A novel fluorescent label based on biological fluorescent NPs and its application in cell recognition, Chinese Science Bulletin, 2001, 46(23): 1962–1965.
He, X. X., Wang, K. M., Tan, W. H. et al., A novel gene carrier based on amino-modified silica NPs, Chinese Science Bulletin, 2003, 48(3): 223–228.
Ye, Z., Tan, M., Wang, G. et al., Preparation, characterization, and time-resolved fluorometric application of silica-coated Terbium (III) fluorescent NPs, Anal. Chem., 2004, 76(3): 513–518.
Santra, S., Tapec, R., Theodoropoulou, N. et al., Synthesis and characterization of silica-coated iron oxide NPs in microemulsion: The effect of nonionic surfactants, Langmuir., 2001, 17(10): 2900–2906.
López Pérez, J. A., López Quintela, M. A., Charles, S. W. et al., Advance in the preparation of magnetic NPs by the microemulsion method, J. Phys. Chem. B, 1997, 101: 8045–8047.
Duan, J. H., Wang, K. M., Tan, W. H. et al., A study of a novel organic fluorescent core-shell NPs, Chemical Journal of Chinese University (in Chinese), 2003, 24(2): 255–259.
Arriagada, F. J., Osseo Asare, K., Synthesis of nanosize silica in a nonionic water-in-oil microemulsion: Effect of the water/surfactant molar ratio and ammonia concentration, J. Colloid Interface Sci., 1999, 211:210–220.
Zhang, J. H., Jiang, Z. H., Wang, R. Z. et al., Preparation of magnetic microparticles, Chemistry (in Chinese), 1997, 9: 55–57.
Author information
Authors and Affiliations
Corresponding author
About this article
Cite this article
He, X., Wang, K., Tan, W. et al. Study on the effect of electrostatic interaction on core-shell nanoparticles preparation with microemulsion technique. Chin.Sci.Bull. 50, 2821–2826 (2005). https://doi.org/10.1360/982005-689
Received:
Accepted:
Issue Date:
DOI: https://doi.org/10.1360/982005-689