Abstract
Carboxyl ion (COOH+) implantation was performed at 50 keV with different fluences for polypropylene. Hemocompatibility tests show that blood coagulation time and recalcification time of polypropylene were enhanced significantly with the increasing fluence. At the same time, the human endothelial cells grown on the surface of the implanted samples exhibited normal cellular growth and morphology. X-ray photoelectron spectroscopy and water contact angle analysis showed that COOH+ ion implantation rearranges chemical bonds and produces some new polar O-containing groups on the surface. The formation of polar functional groups, together with increase of roughness, induced an increase in hydrophilicity, which in turn improved the surface hemocompatibility of polypropylene.
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Suzuki, Y., Kusakabe, M., Kaibara, M. et al., Cell adhesion control by ion implantation into extra-cellular matrix. Nucl. Instr. Meth., 1994, B91: 588.
Tsuji, H., Satoh, H., Ikeda, S. et al., Contact angle lowering of polystyrene surface by silver-negative-ion implantation for improving biocompatibility and introduced atomic bond evaluation by XPS, Nucl. Instr. Meth., 1998, B114: 197.
Koh, S. K., Choi, K. W., Cho, J. S. et al., Ar+ ion irradiation in oxygen environment for improving wettability of polymethylmethacry late, J. Mater. Res., 1996, 11: 2933.
Li, D. J., Cui, F. Z., Gu, H. Q., F+ ion implantation induced cell attachment on intraocular less. Biomaterials, 1999, 20: 1889.
Sun, Y., Li, C., Zhu, Z. et al., Surface modification of polyethylene terephthalate implanted by argon ions. Nucl. Instr. Meth., 1998, B135: 517.
Lhoest, J. B., Dewez, J. L., Bertrand, P., PMMA surface modification under keV and MeV ion bombardment in relation to mammalian cell adhesion. Nucl. Instr. Meth., 1995, B105: 322.
Tsuji, H., Satoh, H., Ikeda, S. et al., Surface modification by silver-negative-ion implantation for controlling cell-adhesion properties of polystyrene, Surf. Coat. Technol., 1998, 103–104: 124.
Cui, F. Z., Luo, Z. S., Biomaterials modification by ion-beam processing, Surf. Coat. Technol., 1999, 112: 278.
Bernacca, G. M., Gulbransen, M. G., Wilkinson, R. et al., In vitro blood compatibility of surface-modified polyurethanes, Biomaterials, 1998, 19: 1151.
Li, D. J., Zhao, J., Gu, H. Q. et al., Surface modification of medical polyurethane by silicon ion bombardment, Nucl. Instr. Meth., 1993, B82: 57.
Li, D. J., Cui, F. Z., Feng, Q. L. et al., Oxygen ion beam and plasma induced blood compatibility of polyetherurethane, Chin. Phys. Lett., 1997, 14: 531.
Li, D. J., Cui, F. Z., Gu, H. Q. et al., Ion-beam-induced biomedical behavior of hexamethyldisiloxane films on deposited polyetherurethanes. Appl. Surf. Sci., 1998, 126: 1.
Li, D. J., Cui, F. Z., Gu, Q. F+ ion implantation induced cell attachment on introcular lens, Biomaterials, 1999, 20: 1889.
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Li, D., Niu, L. Effects of COOH+ ion implantation on hemocompatibility of polypropylene. Sci. China Ser. E-Technol. Sci. 45, 666–670 (2002). https://doi.org/10.1360/02ye9076
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DOI: https://doi.org/10.1360/02ye9076