Skip to main content

Advertisement

SpringerLink
Log in

Outcomes of Single Node Excision Compared with Lymph Node Dissection for Patients with Clinical Stage III N1b Cutaneous Melanoma

  • Aso Research Letter
  • Published:
Annals of Surgical Oncology Aims and scope Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1

References

  1. Sharon CE, Straker RJ, Li EH, Karakousis GC, Miura JT. National practice patterns in the management of the regional lymph node basin after positive sentinel lymph node biopsy for cutaneous melanoma. Ann Surg Oncol. 2022. https://doi.org/10.1245/s10434-022-12364-9.

    Article  PubMed  PubMed Central  Google Scholar 

  2. Faries MB, Thompson JF, Cochran AJ, et al. Completion dissection or observation for sentinel-node metastasis in melanoma. N Engl J Med. 2017;376(23):2211–22. https://doi.org/10.1056/NEJMoa1613210.

    Article  PubMed  PubMed Central  Google Scholar 

  3. Leiter U, Stadler R, Mauch C, et al. Complete lymph node dissection versus no dissection in patients with sentinel lymph node biopsy positive melanoma (DeCOG-SLT): a multicentre, randomised, phase 3 trial. Lancet Oncol. 2016;17(6):757–67. https://doi.org/10.1016/S1470-2045(16)00141-8.

    Article  PubMed  Google Scholar 

  4. Coit DG, Thompson JA, Albertini MR, et al. Cutaneous melanoma, Version 2.2019, NCCN clinical practice guidelines in oncology. J Natl Compr Canc Netw. 2019;17(4):367–402. https://doi.org/10.6004/jnccn.2019.0018.

    Article  CAS  PubMed  Google Scholar 

  5. Kwak M, Song Y, Gimotty PA, et al. Characteristics associated with pathologic nodal burden in patients presenting with clinical melanoma nodal metastasis. Ann Surg Oncol. 2019;26(12):3962–71. https://doi.org/10.1245/s10434-019-07694-0.

    Article  PubMed  PubMed Central  Google Scholar 

Download references

Funding

Dr. Gimotty and Dr. Karakousis’ efforts were funded by the SPORE in Skin Cancer, P50 CA 261608.

Author information

Authors and Affiliations

  1. Division of Endocrine and Oncologic Surgery, Department of Surgery, Hospital of the University of Pennsylvania, 3400 Spruce Street, Maloney 4, Philadelphia, PA, 19104, USA

    Cimarron E. Sharon MD, Gabriella N. Tortorello MD, John T. Miura MD & Giorgos C. Karakousis MD

  2. Department of Biostatistics, Epidemiology, and Informatics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA

    Phyllis A. Gimotty PhD

  3. Division of Surgical Oncology, Department of Surgery, Duke University, Durham, NC, USA

    Georgia M. Beasley MD, MHSc

  4. Division of Breast and Melanoma Surgery, Department of Surgery, University of Virginia, Charlottesville, VA, USA

    Craig L. Slingluff Jr MD

Authors
  1. Cimarron E. Sharon MD
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Gabriella N. Tortorello MD
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Phyllis A. Gimotty PhD
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Georgia M. Beasley MD, MHSc
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. Craig L. Slingluff Jr MD
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. John T. Miura MD
    View author publications

    You can also search for this author in PubMed Google Scholar

  7. Giorgos C. Karakousis MD
    View author publications

    You can also search for this author in PubMed Google Scholar

Contributions

CS had full access to the data and takes responsibility for the integrity of the data and the accuracy of the analyses. Study conception or design: S, T, B, S, M, K. Data acquisition, analysis, or interpretation: S, T, G, M, K. Drafting or critically revising the work: S, T, G, B, S, M, K.

Corresponding author

Correspondence to Cimarron E. Sharon MD.

Ethics declarations

Disclosures

Craig Slingluff, Jr. Intellectual Property—Patents & Copyrights - We have defined a gene expression profile that appears to identify patients who have only one node containing metastatic melanoma. We have submitted a disclosure to our institutional patent office for it, but it is not directly affected by the present work. Giorgos Karakousis Advisory Board-Merck

Additional information

Publisher's Note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Supplementary Information

Below is the link to the electronic supplementary material.

Supplementary file1 (DOCX 20 KB)

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Sharon, C.E., Tortorello, G.N., Gimotty, P.A. et al. Outcomes of Single Node Excision Compared with Lymph Node Dissection for Patients with Clinical Stage III N1b Cutaneous Melanoma. Ann Surg Oncol 30, 1956–1959 (2023). https://doi.org/10.1245/s10434-022-12999-8

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1245/s10434-022-12999-8

Search

Navigation