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ASO Author Reflections: Changes in the Gustave Roussy Immune Score is an Important Biomarker for Therapeutic Sensitivity of Nivolumab in Gastric Cancer

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References

  1. Kang YK, Boku N, Satoh T, et al. Nivolumab in patients with advanced gastric or gastro-oesophageal junction cancer refractory to, or intolerant of, at least two previous chemotherapy regimens (ONO-4538-12, ATTRACTION-2): a randomised, double-blind, placebo-controlled, phase 3 trial. Lancet. 2017;390:2461–71.

    Article  CAS  Google Scholar 

  2. Bigot F, Castanon E, Baldini C, et al. Prospective validation of a prognostic score for patients in immunotherapy phase I trials: the Gustave Roussy Immune Score (GRIm-Score). Eur J Cancer. 2017;84:212–8.

    Article  CAS  Google Scholar 

  3. Nakazawa N, Sohda M, Ubukata Y, et al. Changes in the Gustave Roussy Immune Score as a powerful prognostic marker of the therapeutic sensitivity of nivolumab in advanced gastric cancer: a multicenter retrospective study. Ann Surg Oncol. 2022. https://doi.org/10.1245/s10434-022-12226-4.

    Article  PubMed  Google Scholar 

  4. Janjigian YY, Shitara K, Moehler M, et al. Nivolumab plus chemotherapy versus chemotherapy as first-line treatment for advanced gastric cancer/gastroesophageal junction cancer/oesophageal adenocarcinoma (CheckMate 649): a multicentre, randomised, open-label, phase 3 trial. Lancet. 2021;398:27–40.

    Article  CAS  Google Scholar 

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Correspondence to Nobuhiro Nakazawa MD, PhD.

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Nakazawa, N., Sano, A., Sohda, M. et al. ASO Author Reflections: Changes in the Gustave Roussy Immune Score is an Important Biomarker for Therapeutic Sensitivity of Nivolumab in Gastric Cancer. Ann Surg Oncol 29, 7407–7408 (2022). https://doi.org/10.1245/s10434-022-12233-5

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  • DOI: https://doi.org/10.1245/s10434-022-12233-5

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