References
Cristofanilli M, Budd GT, Ellis MJ, Stopeck A, Matera J, Miller MC, et al. Circulating tumor cells, disease progression, and survival in metastatic breast cancer. N Engl J Med. 2004;351(8):781–91.
Bidard FC, Jacot W, Kiavue N, Dureau S, Kadi A, Brain E, et al. Efficacy of Circulating Tumor Cell Count-Driven vs Clinician-Driven First-line Therapy Choice in Hormone Receptor-Positive, ERBB2-Negative Metastatic Breast Cancer: The STIC CTC Randomized Clinical Trial. JAMA Oncol. 2021;7(1):34–41.
Ring A, Campo D, Porras TB, Kaur P, Forte VA, Tripathy D, et al. Circulating tumor cell transcriptomics as biopsy-surrogates in metastatic breast cancer. Ann Surg Oncol. 2021. https://doi.org/10.1245/s10434-021-11135-2
Siegel MB, He X, Hoadley KA, Hoyle A, Pearce JB, Garrett AL, et al. Integrated RNA and DNA sequencing reveals early drivers of metastatic breast cancer. J Clin Invest. 2018;128(4):1371–83.
Gkountela S, Castro-Giner F, Szczerba BM, Vetter M, Landin J, Scherrer R, et al. Circulating tumor cell clustering shapes DNA methylation to enable metastasis seeding. Cell. 2019;176(1–2):98–112.
Garralda E, Dienstmann R, Piris-Giménez A, et al. New clinical trial designs in the era of precision medicine. Mol Oncol. 2019;13(3):549–57.
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Alexander Ring and Julie E. Lang declare no competing interest for the presented study. Although ANGLE plc provided research funds to the author’s institution, the authors have no relevant financial disclosures. The study sponsor did not influence data acquisition and analysis or the decision to publish.
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Ring, A., Lang, J.E. ASO Author Reflections: Advancing Circulating Tumor Cells as Liquid Biopsies to Efficiently Target Metastatic Breast Cancer. Ann Surg Oncol 29, 2895–2896 (2022). https://doi.org/10.1245/s10434-021-11139-y
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DOI: https://doi.org/10.1245/s10434-021-11139-y