Skip to main content

Advertisement

SpringerLink
Log in

Is Axillary Radiation not Inferior to Axillary Dissection for Sentinel Lymph Node-Positive Breast Cancer After Neoadjuvant Chemotherapy?

  • ASO Research Letter
  • Published:
Annals of Surgical Oncology Aims and scope Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

References

  1. Giuliano AE, Hunt KK, Ballman KV, et al. Axillary dissection vs no axillary dissection in women with invasive breast cancer and sentinel node metastasis: a randomized clinical trial. JAMA. 2011;305(6):569–75.

    Article  CAS  Google Scholar 

  2. Donker M, van Tienhoven G, Straver ME, et al. Radiotherapy or surgery of the axilla after a positive sentinel node in breast cancer (EORTC 10981–22023 AMAROS): a randomised, multicentre, open-label, phase 3 non-inferiority trial. Lancet Oncol. 2014;15(12):1303–10.

    Article  Google Scholar 

  3. Spring LM, Fell G, Arfe A, et al. Pathologic complete response after neoadjuvant chemotherapy and impact on breast cancer recurrence and survival: a comprehensive meta-analysis. Clin Cancer Res. 2020;26(12):2838–48.

    Article  Google Scholar 

  4. Boughey JC, Suman VJ, Mittendorf EA, et al. Sentinel lymph node surgery after neoadjuvant chemotherapy in patients with node-positive breast cancer: the ACOSOG Z1071 (Alliance) clinical trial. JAMA. 2013;310(14):1455–61.

    Article  CAS  Google Scholar 

  5. Piltin MA, Hoskin TL, Day CN, Davis J Jr, Boughey JC. Oncologic outcomes of sentinel lymph node surgery after neoadjuvant chemotherapy for node-positive breast cancer. Ann Surg Oncol. 2020;27(12):4795–801.

    Article  Google Scholar 

  6. Murphy BL, Jakub JW, Asaad M, et al. Sentinel lymph node removal after neoadjuvant chemotherapy in clinically node-negative patients: when to stop? Ann Surg Oncol. 2021;28(2):888–93.

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Surgical Oncology Program, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA

    Tahsin M. Khan MD, Alexander J. Rossi MD & Jonathan M. Hernandez MD

  2. Alliance Statistics and Data Center, Mayo Clinic, Rochester, MN, USA

    Vera Suman PhD

  3. Rutgers Cancer Institute of New Jersey, New Brunswick, NJ, USA

    Bruce Haffty MD

  4. Department of Surgery, Mayo Clinic, Rochester, MN, USA

    Judy C. Boughey MD

Authors
  1. Tahsin M. Khan MD
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Alexander J. Rossi MD
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Vera Suman PhD
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Bruce Haffty MD
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. Jonathan M. Hernandez MD
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. Judy C. Boughey MD
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Judy C. Boughey MD.

Ethics declarations

Disclosures

The authors declare they have no conflicts of interest and nothing to disclose. The NCI provides funding to support the clinical trial A11202. Dr Boughey has research funding from Lilly for clinical trial and receives funding from Cairns Surgical for DSMB work, both unrelated to this article.

Additional information

Publisher's Note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Supplementary Information

Below is the link to the electronic supplementary material.

Supplementary file1 (DOCX 166 kb)

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Khan, T.M., Rossi, A.J., Suman, V. et al. Is Axillary Radiation not Inferior to Axillary Dissection for Sentinel Lymph Node-Positive Breast Cancer After Neoadjuvant Chemotherapy?. Ann Surg Oncol 29, 1526–1527 (2022). https://doi.org/10.1245/s10434-021-10830-4

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1245/s10434-021-10830-4

Search

Navigation