Abstract
Background
Long lags exist in adoption and uptake of evidence-based interventions into real-world clinical practice based on oncology clinical trial results. Implementation science (IS) is a distinct field of health services research that aims to understand the barriers related to adoption of evidence-based guidelines and research in clinical practice.
Methods
Use of IS study design, methods, and outcomes can be elusive to surgical oncologists despite the tremendous need for the application of IS to bridge the evidence-to-practice gap. This report describes key components of high-quality IS.
Results
Herein, we illustrate how IS can be used in surgical oncology practice. Examples from implementation of the breast cancer Short Stay Program (SSP) in Netherlands is used to illustrate IS methods. Specific funding and training opportunities in implementation science are described in detail.
Conclusion
Use of IS in surgical oncology can help improve the uptake of evidence based medicine.
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References
Contopoulos-Ioannidis DG, Alexiou GA, Gouvias TC, Ioannidis JPA. Life cycle of translational research for medical interventions. Science. 2008;321:1298–9.
Chow Z, Gan T, Chen Q, et al. Non-adherence to standard of care for locally advanced colon cancer as a contributory factor for high mortality rates in Kentucky. J Am Coll Surg. 2020;230:428–39.
Jaap K, Fluck M, Hunsinger M, et al. Analyzing the impact of compliance with national guidelines for pancreatic cancer care using the National Cancer Database. J Gastrointest Surg. 2018;22:1358–64.
Trochim WM, McLinden D. Introduction to a special issue on concept mapping. Eval Program Plann. 2017;60:166–75.
Mitchell SA, Chambers DA. Leveraging implementation science to improve cancer care delivery and patient outcomes. J Oncol Pract. 2017;13:523–9.
de Kok M, Frotscher CN, van der Weijden T, et al. Introduction of a breast cancer care programme including ultra short hospital stay in 4 early adopter centres: framework for an implementation study. BMC Cancer. 2007;7:117.
Rabin BA, Brownson RC, Haire-Joshu D, Kreuter MW, Weaver NL. A glossary for dissemination and implementation research in health. J Public Health Manag Pract. 2008;14:117–23.
Peters DH, Adam T, Alonge O, Agyepong IA, Tran N. Implementation research: what it is and how to do it. BMJ. 2013;347:f6753.
Smith AB, Brooke BS. How implementation science in surgery is done. JAMA Surg. 2019;154:891–2.
Glasgow RE, Chambers D. Developing robust, sustainable, implementation systems using rigorous, rapid, and relevant science. Clin Transl Sci. 2012;5:48–55.
Ament S, Gillissen F, Maessen J, van der Weijden T, von Meyenfeldt M, Dirksen CD. Towards a framework for analysing sustainability of economic value: the case of a short stay programme for breast cancer surgery care five years after implementation. Value Health. 2014;17:A662–3.
Ament SM, de Kok M, van de Velde CJ, et al. A detailed report of the resource use and costs associated with implementation of a short stay programme for breast cancer surgery. Implement Sci. 2015;10:78.
Ament SMC, Gillissen F, Moser A, et al. Factors associated with sustainability of 2 quality improvement programs after achieving early implementation success: a qualitative case study. J Eval Clin Pract. 2017;23:1135–43.
de Kok M, Dirksen CD, Kessels AG, et al. Cost-effectiveness of a short stay admission programme for breast cancer surgery. Acta Oncol. 2010;49:338–46.
de Kok M, Scholte RW, Sixma HJ, et al. The patient’s perspective of the quality of breast cancer care: the development of an instrument to measure quality of care through focus groups and concept mapping with breast cancer patients. Eur J Cancer. 2007;43:1257–64.
de Kok M, van der Weijden T, Kessels A, et al. Implementation of an ultra-short-stay program after breast cancer surgery in four hospitals: perceived barriers and facilitators. World J Surg. 2008;32:2541–8.
de Kok M, van der Weijden T, Kessels AG, et al. Patients’ opinions on quality of care before and after implementation of a short stay programme following breast cancer surgery. Breast. 2010;19:404–9.
de Kok M, van der Weijden T, Voogd AC, et al. Implementation of a short-stay programme after breast cancer surgery. Br J Surg. 2010;97:189–94.
Helfrich CD, Damschroder LJ, Hagedorn HJ, et al. A critical synthesis of literature on the promoting action on research implementation in health services (PARIHS) framework. Implement Sci. 2010;5:82.
Stetler CB, Damschroder LJ, Helfrich CD, Hagedorn HJ. A guide for applying a revised version of the PARIHS framework for implementation. Implement Sci. 2011;6:99.
Tabak RG, Chambers DA, Hook M, Brownson RC. The conceptual basis for dissemination and implementation research: lessons from existing models and frameworks. In: Dissemination and Implementation Research in Health. 2 ed. Oxford University Press, New York, 2017.
Cane J, O’Connor D, Michie S. Validation of the theoretical domains framework for use in behaviour change and implementation research. Implement Sci IS. 2012;7:37.
Huijg JM, Gebhardt WA, Crone MR, Dusseldorp E, Presseau J. Discriminant content validity of a theoretical domains framework questionnaire for use in implementation research. Implement Sci. 2014;9:11.
Damschroder LJ, Aron DC, Keith RE, Kirsh SR, Alexander JA, Lowery JC. Fostering implementation of health services research findings into practice: a consolidated framework for advancing implementation science. Implement Sci. 2009;4:50.
Wensing M, Bosch M, Grol R. Determinants of change. Improving Patient Care: The Implementation of Change in Health Care. Second Edition. Oxford, United Kingdom: John Wiley & Sons. 2013. p.137–150.
Wensing M, Bosch M, Grol R. Methods to identify determinants of change in healthcare. Improving Patient Care: The Implementation of Change in Health Care. Second Edition. Oxford, United Kingdom: John Wiley & Sons. 2013. p.151–164.
Harvey G, Kitson A. PARIHS revisited: from heuristic to integrated framework for the successful implementation of knowledge into practice. Implement Sci. 2016;11:33.
Kitson A, Harvey G. Implementing evidence-based practice in healthcare: a facilitation guide. Milton Park: Routledge; 2015.
Grol R, Bosch M, Wensing M. Development and selection of strategies for improving patient care. Improving Patient Care: The Implementation of Change in Health Care. Second Edition. Oxford, United Kingdom: John Wiley & Sons. 2013. p. 165–184.
Kok G, Gottlieb NH, Peters G-JY, et al. A taxonomy of behaviour change methods: an Intervention Mapping approach. Health Psychol Rev. 2016;10:297–312.
Kok G, Peters LWH, Ruiter RA. Planning theory- and evidence-based behavior change interventions: a conceptual review of the intervention mapping protocol. Psicol Reflex Crít. 2017;30:19.
Implementation Science at a Glance: A Guide for Cancer Control Practitioners. Retrieved 27 February 2020 at https://cancercontrolplanet.cancer.gov/planet.
Proctor E, Silmere H, Raghavan R, et al. Outcomes for implementation research: conceptual distinctions, measurement challenges, and research agenda. Administr Policy Mental Health Mental Health Serv Res. 2011;38:65–76.
Scheirer MA, Dearing JW. An agenda for research on the sustainability of public health programs. Am J Public Health. 2011;101:2059–67.
Ament SMC, Gillissen F, Maessen JMC, et al. Sustainability of short stay after breast cancer surgery in early adopter hospitals. Breast. 2014;23:429–34.
Scheirer MA. Is sustainability possible? A review and commentary on empirical studies of program sustainability. Am J Eval. 2005;26:320–47.
Severens JL. Value for money of changing healthcare services? Economic evaluation of quality improvement. Qual Saf Health Care. 2003;12:366–71.
Curran GM, Bauer M, Mittman B, Pyne JM, Stetler C. Effectiveness-implementation hybrid designs: combining elements of clinical effectiveness and implementation research to enhance public health impact. Med Care. 2012;50:217–26.
Singal AG, Higgins PDR, Waljee AK. A primer on effectiveness and efficacy trials. Clin Transl Gastroenterol. 2014;5:e45.
Brown CH, Curran G, Palinkas LA, et al. An overview of research and evaluation designs for dissemination and implementation. Annu Rev Public Health. 2017;38:1–22.
Vinson CA, Clyne M, Cardoza N, Emmons KM. Building capacity: a cross-sectional evaluation of the US Training Institute for Dissemination and Implementation Research in Health. Implement Sci. 2019;14:97.
Meissner HI, Glasgow RE, Vinson CA, et al. The US training institute for dissemination and implementation research in health. Implement Sci. 2013;8:12.
Neta G, Sanchez MA, Chambers DA, et al. Implementation science in cancer prevention and control: a decade of grant funding by the National Cancer Institute and future directions. Implement Sci. 2015;10:4.
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Electra Paskett's intitution receives grants for work in which she is the multi-institution PI. The grants are funded by Merck Foundation, Pfizer, and the Breast Cancer Research Foundation. The remaining authors have no conflicts of interest.
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Park, K.U., Birken, S., Garvin, J. et al. Practical Guide to Implementation Science for Surgical Oncologists: Case Study of Breast Cancer Short Stay Program. Ann Surg Oncol 29, 699–705 (2022). https://doi.org/10.1245/s10434-021-10479-z
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DOI: https://doi.org/10.1245/s10434-021-10479-z