Skip to main content

Advertisement

Log in

Salvage Surgery for Jejunal Necrosis After a Free Jejunal Transfer

  • Reconstructive Oncology
  • Published:
Annals of Surgical Oncology Aims and scope Submit manuscript

Abstract

Introduction

Given the few reports regarding the salvage methods for managing jejunal necrosis, finding candidates for a meta-analysis or systematic review is difficult. Thus, this study aimed to describe the interventions for jejunal necrosis and investigate important points relating to this condition.

Methods

The interventions used to treat free jejunal necrosis are external fistula formation with jejunal debridement, secondary reconstruction of the local site, and overall status improvement, and re-free jejunal transfer with removal of the necrotic jejunum. Selecting the optimal procedure for each patient depends on the following factors. First, patients must have a good overall status to be able to endure re-free jejunal transfer, and next, the procedure is also dependent on local factors, including the intensity of the infections of the postoperative wound.

Results

One of the most common factors of jejunal necrosis is necrosis due to blood flow deficiency of the transferred tissue. However, among jejunal necrotic cases, some patients had no blood circulation disorder. We inferred that a non-occlusive mesenteric ischemia like occurred in the transferred jejunum, and also considered patients’ overall status and necrotic association. Thus, patients who underwent re-free jejunal transfer are at an increased risk of experiencing re-necrosis. Based on these findings, we designed a jejunal necrosis algorithm.

Conclusions

Early debridement and re-free jejunal transfer are optimal treatment options for patients with early-stage jejunal necrosis. Because re-jejunum transfer is a possible state after necrosis, it was thought that coping was the most important aspect of detection at an early stage.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1
Fig. 2

References

  1. Seidenberg B, Rosenak SS, Hurwitt ES, et al. Immediate reconstruction of the cervical esophagus by a revascularized isolated jejunal segment. Ann Surg. 1959;149(2):162–71.

    Article  CAS  Google Scholar 

  2. McKee DM, Peters CR. Reconstruction of the hypopharynx and cervical esophagus with microvascular jejunal transplant. Clin Plast Surg. 1978;5(2);305–12.

    CAS  PubMed  Google Scholar 

  3. Reece GP, Bengtson BP, Schusterman MA, et al. Reconstruction of the pharynx and cervical esophagus using free jejunal transfer. Clin Plast Surg. 1994;21(1);125–36.

    CAS  PubMed  Google Scholar 

  4. Okazaki M, Asato H, Takushima A, Nakatsuka T, Ueda K, Harii K. Secondary reconstruction of failed esophageal reconstruction. Ann Plast Surg. 2005;54(5):530–7.

    Article  CAS  Google Scholar 

  5. Oki M, Asato H, Suzuki Y, et al. Salvage reconstruction of the oesophagus: a retrospective study of 15 cases. J Plast Reconstr Aesthet Surg. 2010;63(4);589–97.

    Article  Google Scholar 

  6. Kadota H, Sakuraba M, Kimata Y, et al. Larynx-preserving esophagectomy and jejunal transfer for cervical esophageal carcinoma. Laryngoscope. 2009;119(7);1274–80.

    Article  Google Scholar 

  7. Nakatsuka T, Harii K, Ueda K, et al. Preservation of the larynx after resection of a carcinoma of the posterior wall of the hypopharynx: versatility of a free flap patch graft. Head Neck. 1997;19(2);137–42.

    Article  CAS  Google Scholar 

  8. Ida S, Morita M, Hiyoshi Y, Ikeda K, Ando K, Kimura Y, et al. Surgical resection of hypopharynx and cervical esophageal cancer with a history of esophagectomy for thoracic esophageal cancer. Ann Surg Oncol. 2014;21(4):1175–81.

    Article  Google Scholar 

  9. Keereweer S, Sewnaik A, Kerrebijn J, et al. Salvage or what follows the failure of a free jejunum transfer for reconstruction of the hypopharynx? J Plast Reconstr Aesthet Surg. 2010;63(6):976–80.

    Article  CAS  Google Scholar 

  10. Ni S, Zhu Y, Wang J, Li D, Zhang B, Xu Z, Liu S. Salvage Procedures after Total Necrosis of a Free Jejunal Graft. ORL J Otorhinolaryngol Relat Spec. 2015;77(5):262–7.

    Article  Google Scholar 

  11. Umezawa H, Matsutani T, Ogawa R, Hyakusoku H. Immediate free jejunum transfer for salvage surgery of gastric tube necrosis. Case Rep Gastrointest Med. 2014;2014:327549.

    PubMed  PubMed Central  Google Scholar 

  12. Okazaki M, Asato H, Takushima A, et al. Analysis of salvage treatments following the failure of free flap transfer caused by vascular thrombosis in reconstruction for head and neck cancer. Plast Reconstr Surg. 2007;119:1223–32.

    Article  CAS  Google Scholar 

  13. Fujiki M, Miyamoto S, Sakuraba M, Nagamatsu S, Hayashi R. Risk factors for tracheal necrosis after total pharyngolaryngectomy. Head Neck. 2015;37(8):1207–10.

    Article  Google Scholar 

  14. Onoda S, Kimata Y, Yamada K, et al. The best salvage operation method after total necrosis of a free jejunal graft? Transfer of a second free jejunal graft. J Plast Reconstr Aesthet Surg. 2011;64(8):1030–4.

    Article  Google Scholar 

  15. Bertino G, Benazzo M, Occhini A, et al. Reconstruction of the hypopharynx after free jejunum flap failure: is a second free jejunum transfer feasible? Oral Oncol. 2008;44(1);61–4.

    Article  Google Scholar 

  16. Harashina T. Use of a continuous suture for back wall repair of end-to-end or end-to-side anastomoses. Plast Reconstr Surg. 1982;69:139–44.

    Article  CAS  Google Scholar 

  17. Nagata T, Masumoto K, Watanabe Y, Katou F. End-to-side anastomosis to the external jugular vein: preservation of external jugular vein blood flow. Br J Oral Maxillofac Surg. 2012;50(2):e31–2.

    Article  Google Scholar 

  18. Onoda S, Kimata Y, Goto A. The drop-down technique as an optimal technique for back-wall end-to-side anastomosis. J Craniofac Surg. 2014;25(4):1435–7.

    Article  Google Scholar 

  19. Miyamoto S, Okazaki M, Takushima A, Shiraishi T, Omori M, Harii K. Versatility of a posterior-wall-first anastomotic technique using a short-thread double-needle microsuture for atherosclerotic arterial anastomosis. Microsurgery. 2008;28(7):505–8.

    Article  Google Scholar 

  20. Nakagawa M, Inoue K, Iida T, Asano T. A modified technique of end-to-side microvascular anastomosis for the posterior wall. J Reconstr Microsurg. 2008;24(7):475–8.

    Article  Google Scholar 

  21. Kurita T, Kubo T, Tashima H, Fujii T. Free jejunal flap transfer with multiple vascular pedicles for safe and reliable pharyngoesophageal reconstruction. Head Neck. 2018;40(10):2210–2218.

    Article  Google Scholar 

  22. Onoda S, Kimata Y, Yamada K, Koshimune S, Onoda T, Shirakawa Y. Non-occlusive mesenteric ischaemia of a free jejunal flap. J Plast Reconstr Aesthet Surg. 2013;66(5):e133–6.

    Article  Google Scholar 

  23. Carrie C, Gisbert-Mora C, Quinart A, et al. Non-occlusive mesenteric ischemia detected by ultrasound. Intensive Care Med. 2012;38(2):333–4.

    Article  Google Scholar 

  24. Qureshi SS, Neve RS, Raina SA, et al. Fatal non-occlusive mesenteric ischemia after esophagectomy. J Cancer Res Ther. 2010;6(1):112–3.

    Article  Google Scholar 

  25. Wilcox MG, Howard TJ, Plaskon LA, et al. Current theories of pathogenesis and treatment of nonocclusive mesenteric ischemia. Dig Dis Sci. 1995;40:709–16.

    Article  CAS  Google Scholar 

  26. Bassilios N, Menoyo V, Berger A, et al. Mesenteric ischemia in hemodialysis patients: a case/control study. Nephrol Dial Transplant. 2003;18:911–7.

    Article  Google Scholar 

  27. Minko P, Groesdonk H, Stroeder J, et al. A scoring system for the assessment of angiographic findings in non-occlusive mesenteric ischemia (NOMI). Rofo. 2012;184(9):805–9.

    Article  CAS  Google Scholar 

  28. Harris JR, Lueg E, Genden E, Urken ML. The thoracoacromial/cephalic vascular system for microvascular anastomoses in the vesseldepleted neck. Arch Otolaryngol Head Neck Surg. 2002;128:319–23.

    Article  Google Scholar 

  29. Kompatscher P, Manestar M, Schuster A, Lang A, Beer GM. The thoracoacromial vessels as recipient vessels in microsurgery and supermicrosurgery: an anatomical and sonographic study. Plast Reconstr Surg. 2005;115:77–83.

    CAS  PubMed  Google Scholar 

  30. Onoda S, Sakuraba M, Asano T, Miyamoto S, Hayashi R, Asai M, et al. Thoracoacromial vessels as recipients for head and neck reconstruction and cause of vascular complications. Microsurgery. 2011;31(8):628–31.

    Article  Google Scholar 

  31. Moran SL, Nava G, Behnam AB, Serletti JM. An outcome analysis comparing the thoracodorsal and internal mammary vessels as recipient sites for microvascular breast reconstruction: a prospective study of 100 patients. Plast Reconstr Surg. 2003;111(6):1876–82.

    Article  Google Scholar 

  32. Clark CP 3rd, Rohrich RJ, Copit S, Pittman CE, Robinson J. An anatomic study of the internal mammary veins: clinical implications for free-tissue-transfer breast reconstruction. Plast Reconstr Surg. 1997;99(2):400.

    Article  Google Scholar 

  33. Bafitis H, Stallings JO, Ban J. A reliable method for monitoring the microvascular patency of free jejunal transfers in reconstructing the pharynx and cervical esophagus. Plast Reconstr Surg. 1989;83(5):896–8.

    Article  CAS  Google Scholar 

  34. Katsaros J, Banis JC, Acland RD, et al. Monitoring free vascularised jejunum grafts. Br J Plast Surg. 1985;38(2):220–2.

    Article  CAS  Google Scholar 

  35. Disa JJ, Cordeiro PG, Hidalgo DA. Efficacy of conventional monitoring techniques in free tissue transfer: an 11-year experience in 750 consecutive cases. Plast Reconstr Surg. 1999;104:97–101.

    Article  CAS  Google Scholar 

  36. Dionyssopoulos A, Odobescu A, Foroughi Y, Harris P, Karagergou E, Guertin L, et al. Monitoring buried jejunum free flaps with a sentinel: a retrospective study of 20 cases. Laryngoscope. 2012;122(3):519–22.

    Article  Google Scholar 

  37. Kashimura T, Nakazawa H, Shimoda K, Soejima K. False-negative monitoring flap in free jejunal transfer. J Reconstr Microsurg. 2013;29(2):137–40.

    Article  Google Scholar 

  38. Kadota H, Fukushima J, Kamizono K, Umeno Y, Nakashima T, Yasumatsu R, et al. Selective epithelial ischemia of transferred free jejunum after late loss of its vascular pedicle. Ann Plast Surg. 2011;67(6):612–4.

    Article  CAS  Google Scholar 

  39. Ozkan O, Ozkan O, Bektas G, Cinpolat A, Bassorgun I, Ciftcioglu A. The relationship between ischemia time and mucous secretion in vaginal reconstruction with the jejunal free flap: an experimental study on the rat jejunum. Ann Plast Surg. 2015;75(1):98–101.

    Article  CAS  Google Scholar 

  40. Sakurai H, Nozaki M, Takeuchi M, et al. Monitoring the changes in intraparenchymatous venous pressure to ascertain flap viability. Plast Reconstr Surg. 2007;119(7);2111–7.

    Article  CAS  Google Scholar 

  41. Anthony JP, Singer MI, Mathes SJ. Pharyngoesophageal reconstruction using the tubed free radial forearm flap. Clin Plast Surg. 1994;21:137–141.

    CAS  PubMed  Google Scholar 

  42. Scharpf J, Esclamado RM. Reconstruction with radial forearm flaps after ablative surgery for hypopharyngeal cancer. Head Neck. 2003;25:261–6.

    Article  Google Scholar 

  43. Nakatsuka T, Harii K, Asato H, Ebihara S, et al. Comparative evaluation in pharyngo-oesohageal reconstruction: radial forearm flap compared with jejunal flap. A 10-year experience. Scand J Plast Reconstr Surg Hand Surg. 1998;32(3):307–10.

    Article  CAS  Google Scholar 

  44. Yu P, Lewin JS, Reece GP, et al. Comparison of clinical and functional outcomes and hospital costs following pharyngoesophageal reconstruction with the anterolateral thigh free flap versus the jejunal flap. Plast Reconstr Surg. 2006;117(3):968–74.

    Article  CAS  Google Scholar 

  45. Yu P, Robb GL. Pharyngoesophageal reconstruction with the anterolateral thigh flap: a clinical and functional outcomes study. Plast Reconstr Surg. 2005;116:1845–1855.

    Article  CAS  Google Scholar 

  46. Koshima I, Fukuda H, Yamamato H, Moriguchi T, Soeda S, Ohta S. Free anterolateral thigh flaps for reconstruction of head and neck defects. Plast Reconstr Surg. 1993;92:421–428.

    Article  CAS  Google Scholar 

  47. Parmar S, Al Asaadi Z, Martin T, Jennings C, Pracy P. The anterolateral fasciocutaneous thigh flap for circumferential pharyngeal defects: can it really replace the jejunum? Br J Oral Maxillofac Surg. 2014;52(3):247–50.

    Article  CAS  Google Scholar 

  48. Jiao HS, Shan T, Cheng GL, Pan DD, Chi HF. A novel blood supply method for free jejunal transfer with the third jejunal artery as vascular pedicle. Surg Radiol Anat. 2012;34(10):953–7.

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Satoshi Onoda PhD.

Additional information

Publisher's Note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Onoda, S., Kinoshita, M. Salvage Surgery for Jejunal Necrosis After a Free Jejunal Transfer. Ann Surg Oncol 26, 2122–2126 (2019). https://doi.org/10.1245/s10434-019-07348-1

Download citation

  • Received:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1245/s10434-019-07348-1

Navigation