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Oncologic Outcomes of Self-Expandable Metallic Stent as a Bridge to Surgery and Safety and Feasibility of Minimally Invasive Surgery for Acute Malignant Colonic Obstruction

Annals of Surgical Oncology volume 26, pages 2787–2796 (2019)Cite this article

Abstract

Background

Although self-expandable metal stents (SEMS) are widely used as a bridge to surgery (BTS) in patients with malignant colorectal cancer obstruction, there has been some debate about their effect on long-term oncological outcomes. Furthermore, data on the safety and feasibility of minimally invasive surgery (MIS) combined with stent placement are scarce. We aimed to determine the long-term oncological outcomes of SEMS as a BTS, and the short-term outcomes of SEMS used with minimally invasive colorectal surgery.

Methods

Data from patients who were admitted with malignant obstructing colon cancer between January 2006 and December 2015 were retrospectively reviewed; 71 patients underwent direct surgery and 182 patients underwent SEMS placement as a BTS. Long-term and short-term outcomes of the groups were compared. In a subgroup analysis of the BTS group, the short-term outcomes of conventional open surgery and MIS were compared.

Results

There were no differences in long-term oncologic outcomes between groups. The primary anastomosis rate was higher in the stent group than in the direct surgery group. In the stent group, postoperative complication rates were lower in the minimally invasive group than in the open surgery group. Time to flatus and time to soft diet resumption were shorter in the minimally invasive group, as was length of hospital stay.

Conclusions

Elective surgery after stent insertion does not adversely affect long-term oncologic outcomes. Furthermore, MIS combined with stent insertion for malignant colonic obstruction is safe and feasible.

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Author Contributions

SYY: Data collection and analysis, manuscript writing. YYP: Data collection, critical review. YDH: Data collection, critical review. MSC: Data collection, critical review. HH: Data collection, critical review. BSM: Data collection, critical review. KYL: Data collection, critical review. NKK: Study idea, design, data collection and analysis, manuscript writing

Acknowledgement

The authors would like to thank Dong-Su Jang, MFA (Medical Illustrator) for his help with the illustrations.

Human Rights Statement

All procedures were in accordance with the ethical standards of the responsible committee on human experimentation (institutional and national) and with the Helsinki Declaration of 1964 and later versions. This retrospective study was approved by the Institutional Review Board (IRB) of Severance Hospital, Yonsei University College of Medicine (4-2018-0191).

Informed Consent

Owing to the retrospective nature of the study, signed patient informed consent was waived as per the IRB approval.

Disclosures

Seung Yoon Yang, Youn Young Park, Yoon Dae Han, Min Soo Cho, Hyuk Hur, Byung Soh Min, Kang Young Lee, and Nam Kyu Kim have no disclosures to declare.

Conflict of Interest

All authors have completed the disclosure declaration, and none of the authors or their immediate family members report any conflicting financial interest.

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Affiliations

  1. Division of Colon and Rectal Surgery, Department of Surgery, Severance Hospital, Yonsei University College of Medicine, Seoul, Korea

    Seung Yoon Yang MD, Yoon Dae Han MD, Min Soo Cho MD, Hyuk Hur MD, PhD, Byung Soh Min MD, PhD, Kang Young Lee MD, PhD & Nam Kyu Kim MD, PhD

  2. Department of Surgery, Uijeongbu St. Mary’s Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea

    Youn Young Park MD, PhD

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  1. Seung Yoon Yang MD
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Yang, S.Y., Park, Y.Y., Han, Y.D. et al. Oncologic Outcomes of Self-Expandable Metallic Stent as a Bridge to Surgery and Safety and Feasibility of Minimally Invasive Surgery for Acute Malignant Colonic Obstruction. Ann Surg Oncol 26, 2787–2796 (2019). https://doi.org/10.1245/s10434-019-07346-3

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  • DOI: https://doi.org/10.1245/s10434-019-07346-3