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Timing of Surgical Resection for Curative Colorectal Cancer with Liver Metastasis

  • Colorectal Cancer
  • Published:
Annals of Surgical Oncology Aims and scope Submit manuscript

Abstract

Purpose and Design

Optimal surgical strategy for resectable synchronous colorectal cancer with liver metastasis (SCRLM) remains a therapeutic dilemma. Multiple retrospective studies including several meta-analyses have been published since 2001 to help facilitate the decision making process and identify the optimal surgical approach. Controversy limits the generalization of available data to draw conclusions. A review of available literature on appropriate surgical timing may alleviate confusion among physicians and promote a more evidence based approach.

Results and Conclusion

Current evidence supports the feasibility, safety, and equivalent oncological outcomes of simultaneous curative resection of stage IV colorectal cancer with liver metastasis in appropriately selected patients.

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Author information

Authors and Affiliations

  1. Division of Colon and Rectal Surgery, Mayo Clinic, Rochester, MN, 55905, USA

    Shahzad M. Ali MD

  2. Division of Surgical Oncology, Ohio State University Wexner Medical Center, Columbus, OH, USA

    Shahzad M. Ali MD & Timothy M. Pawlik MD, MPH, PhD, FACS

  3. Colon and Rectal Surgery, The University of Texas, MD Anderson Cancer Center, Houston, TX, USA

    Shahzad M. Ali MD & George J. Chang MD, MS, FACS, FASCRS

  4. The University of Texas, MD Anderson Cancer Center, 1515 Holcombe Blvd, Houston, TX, 77230-1402, USA

    Shahzad M. Ali MD & Miguel A. Rodriguez-Bigas MD, FACS, FASCRS

  5. College of Medicine, University of Central Florida, 2501 North Orange Avenue, Orlando, FL, USA

    Shahzad M. Ali MD, John R.T. Monson MD, FRCS & David W. Larson MD, MBA, FACS, FASCRS

Authors
  1. Shahzad M. Ali MD
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  2. Timothy M. Pawlik MD, MPH, PhD, FACS
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  3. Miguel A. Rodriguez-Bigas MD, FACS, FASCRS
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  4. John R.T. Monson MD, FRCS
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  5. George J. Chang MD, MS, FACS, FASCRS
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  6. David W. Larson MD, MBA, FACS, FASCRS
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Corresponding author

Correspondence to David W. Larson MD, MBA, FACS, FASCRS.

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Ali, S.M., Pawlik, T.M., Rodriguez-Bigas, M.A. et al. Timing of Surgical Resection for Curative Colorectal Cancer with Liver Metastasis. Ann Surg Oncol 25, 32–37 (2018). https://doi.org/10.1245/s10434-016-5745-7

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  • DOI: https://doi.org/10.1245/s10434-016-5745-7

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