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Short- and Long-Term Outcomes After Gastrectomy in Elderly Gastric Cancer Patients

  • Gastrointestinal Oncology
  • Published:
Annals of Surgical Oncology Aims and scope Submit manuscript

Abstract

Background

The number of elderly patients undergoing gastric cancer surgery has recently increased. We therefore evaluated the short- and long-term outcomes of elderly patients after curative gastrectomy.

Methods

Overall, 824 patients were included in this retrospective study, which comprised of a non-elderly group (60–64 years; n = 558), an early-elderly group (75–79 years; n = 198), and a late-elderly group (≥80 years; n = 68) who underwent curative gastrectomy for gastric cancer between 2005 and 2009. Postoperative complications, according to the Clavien–Dindo classification, and survival of both elderly groups were compared with the non-elderly group. Postoperative life expectancy of the late-elderly group was compared with the corresponding aged general population.

Results

Overall and severe (grade III or higher) complications in the early-elderly group were comparable with the non-elderly group; however, those in the late-elderly group were significantly more common than in the non-elderly group (p = 0.013 and p = 0.043, respectively). Multivariable analysis revealed that age ≥80 years was an independent risk factor for severe complications (hazard ratio 3.02, 95 % confidence interval 1.12–8.17; p = 0.029), and the disease-specific survivals of both elderly groups were comparable with the non-elderly group in all TNM stages. Postoperative life expectancy of late-elderly patients eliminating death from recurrence was comparable with the corresponding aged general population eliminating death from gastric cancer.

Conclusions

Gastric cancer surgery in elderly patients aged ≥80 years achieves reasonable long-term survival despite the increased risk of severe complications.

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Disclosure

Jun-Young Yang, Hyuk-Joon Lee, Tae Han Kim, Yeon-Ju Huh, Young-Gil Son, Ji-Ho Park, Hye Seong Ahn, Yun-Suhk Suh, Seong-Ho Kong, and Han-Kwang Yang declare no conflicts of interest.

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Authors and Affiliations

  1. Department of Surgery, Seoul National University College of Medicine, Seoul, Korea

    Jun-Young Yang MD, Hyuk-Joon Lee MD, PhD, Tae Han Kim MD, Yeon-Ju Huh MD, Young-Gil Son MD, PhD, Ji-Ho Park MD, Yun-Suhk Suh MD, Seong-Ho Kong MD, PhD & Han-Kwang Yang MD, PhD

  2. Cancer Research Institute, Seoul National University College of Medicine, Seoul, Korea

    Hyuk-Joon Lee MD, PhD & Han-Kwang Yang MD, PhD

  3. Department of Surgery, Gachon University Gil Medical Center, Incheon, Korea

    Jun-Young Yang MD

  4. Department of Surgery, Keimyung University Dongsan Medical Center, Daegu, Korea

    Young-Gil Son MD, PhD

  5. Department of Surgery, Gyeongsang National University Hospital, Jinju, Korea

    Ji-Ho Park MD

  6. Department of Surgery, Seoul National University Boramae Hospital, Seoul, Korea

    Hye Seong Ahn MD, PhD

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  1. Jun-Young Yang MD
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  2. Hyuk-Joon Lee MD, PhD
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  3. Tae Han Kim MD
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  7. Hye Seong Ahn MD, PhD
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  8. Yun-Suhk Suh MD
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  9. Seong-Ho Kong MD, PhD
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Correspondence to Hyuk-Joon Lee MD, PhD.

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Yang, JY., Lee, HJ., Kim, T.H. et al. Short- and Long-Term Outcomes After Gastrectomy in Elderly Gastric Cancer Patients. Ann Surg Oncol 24, 469–477 (2017). https://doi.org/10.1245/s10434-016-5482-y

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  • DOI: https://doi.org/10.1245/s10434-016-5482-y

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