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The Incidence of Unexpected Uterine Malignancy in Women Undergoing Hysterectomy for a Benign Condition: A National Population-Based Study

  • Gynecologic Oncology
  • Published:
Annals of Surgical Oncology Aims and scope Submit manuscript

Abstract

Background

Potential risks associated with using a laparoscopic power morcellator have been reported in terms of the intraperitoneal seeding of benign and malignant diseases; therefore, knowing the precise incidence of unexpected uterine malignancy (UUM) would have clinically significant value.

Objective

The aim of this study was to investigate the incidence of UUM after a hysterectomy for benign conditions.

Methods

We analyzed the national inpatient sample data that were extracted by a stratified random sampling (sex and age) method from the Korean National Health Insurance Database between 1 January 2010 and 31 December 2012.

Results

Among 1,878,507 women treated during the study period, 12,850 women who underwent a hysterectomy for benign conditions were enrolled in this study. The mean age of these women was 47.22 ± 7.07 years. A laparotomic or laparoscopic hysterectomy was performed in 6623 and 6227 women, respectively, and UUM after hysterectomy was diagnosed in 24 women. No significant difference in the incidence of UUM was noted between the laparotomic and laparoscopic cases [laparotomy, 15 (0.23 %); laparoscopy, 9 (0.14 %); p = 0.28]. The incidence of UUM after hysterectomy was 0.19 % [confidence interval (CI) 0.11–0.26 %]; the incidence of unsuspected endometrial cancer after hysterectomy was 0.12 % (CI 0.06–0.19 %); and the incidence of UUM other than endometrial cancer after hysterectomy was 0.06 % (CI 0.02–0.11 %).

Conclusion

This study shows that the incidence of UUM diagnosed after a hysterectomy for benign conditions was low, but has clinical significance with regard to the potential dissemination of UUM.

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Funding

This article was not supported by any financial funds, and the authors are not affiliated with the instrumental company referred to in the text.

Conflicts of Interest

Jin-Sung Yuk, Log Young Kim, Sang-Hyun Kim, and Jung Hun Lee report no conflicts of interest.

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Authors and Affiliations

  1. Department of Obstetrics and Gynecology, Gyeongsang National University Changwon Hospital, Gyeongsang National University, School of Medicine, Changwon, Republic of Korea

    Jung Hun Lee MD, PhD

  2. Department of Obstetrics and Gynecology, School of Medicine, Eulji University, Daejeon, Republic of Korea

    Jin-Sung Yuk MD, PhD

  3. Department of Obstetrics and Gynecology, MizMedi Hospital, Seoul, Republic of Korea

    Jin-Sung Yuk MD, PhD

  4. The Health Insurance Review and Assessment Service of Korea, Seoul, Republic of Korea

    Log Young Kim MA & Sang-Hyun Kim BS

Authors
  1. Jin-Sung Yuk MD, PhD
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  2. Log Young Kim MA
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  3. Sang-Hyun Kim BS
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  4. Jung Hun Lee MD, PhD
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Corresponding author

Correspondence to Jung Hun Lee MD, PhD.

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Yuk, JS., Kim, L.Y., Kim, SH. et al. The Incidence of Unexpected Uterine Malignancy in Women Undergoing Hysterectomy for a Benign Condition: A National Population-Based Study. Ann Surg Oncol 23, 4029–4034 (2016). https://doi.org/10.1245/s10434-016-5287-z

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  • DOI: https://doi.org/10.1245/s10434-016-5287-z

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