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Rates of Neoadjuvant Chemotherapy and Oncoplastic Surgery for Breast Cancer Surgery: A French National Survey

  • Breast Oncology
  • Published:
Annals of Surgical Oncology Aims and scope Submit manuscript

Abstract

Background

The current retrospective study was intended to obtain up-to-date and comprehensive data on surgical practice for breast cancer throughout France, including neoadjuvant chemotherapy (NAC) and the more recent surgical techniques of oncoplastic surgery (OPS).

Methods

In June 2011, e-mail surveys were sent to 33 nationally renowned breast cancer surgeons from French public or private hospitals. The questionnaire focused on all the new cases of breast cancer treated in 2010. It included questions regarding surgical practices, with special emphases on NAC and OPS and other surgical characteristics.

Results

The overall response rate for the survey was 72.7 %. The total number of breast cancer cases from the survey was 13,762, which constitutes 26.2 % of the total incidence in 2010. Breast-conserving surgery (BCS) was performed for 71.0 % of the patients, and the results were similar throughout the types of practices. Of these patients, 13.9 % received OPS, either upfront or after NAC. Mastectomy was performed for 29.0 % of the patients, which is consistent with French official numbers. Among all patients, 16.3 % underwent surgery after NAC.

Conclusion

To the authors’ knowledge, there are no publications of national figures on NAC or OPS rates to date. They are convinced that this study offers real-life surgical care information on a large population and covers France’s breast cancer surgical landscape. Mastectomy rates in France remain stable and consistent with those in other European countries. However, additional large-scale retrospective studies are required to confirm these figures and further explore NAC and OPS rates as well as surgical practice characteristics.

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Acknowledgment

The authors would thank the following surgeons who contributed to this study: Dr. Jean-Pierre Alfonsi (Clinique Saint-Antoine, Bastia, France), Dr. Séverine Alran (CLCC Institut Curie, Paris, France), Dr. Pierre Azuar (Centre Hospitalier de Grasse, France), Pr. Emmanuel Barranger (Hôpital Lariboisière, Paris, France), Pr. Pascal Bonnier (Hôpital Privé Beauregard, Marseille, France), Pr. Jean-Marc Classe (CRLCC René Gauducheau, Nantes, France), Dr. Krishna Clough and Dr. Claude Nos (Institut du Sein, Paris, France), Dr. Monique Cohen (Clinique la Casamance, Aubagne, France), Pr. Jacques Dauplat, Pr. Christophe Pomel, and Dr. Guillaume Le Bouedec (CRLCC Jean Perrin, Clermont-Ferrand, France), Dr. Pierre-Hervé Dorangeon (Polyclinique Courlancy, Reims, France), Dr. Erwan Du Rouchet (Centre Hospitalier Régional, Orléans, France), Dr. Bernard Flipo (CRLCC Antoine Lacassagne, Nice, France), Dr. Jean-Rémi Garbay (CLCC Gustave Roussy, Villejuif, France), Pr. Sylvia Giard, Dr. Marie-Pierre Chauvet, and Dr. Jean-Louis Houpeau (CRLCC Oscar Lambret, Lille, France), Dr. Gilles Houvenaeghel (CRLCC Paoli-Calmettes, Marseille, France), Pr. Jean-Pierre Lefranc (Hôpital de la Pitié-Salpêtrière, Paris, France), Dr. Christophe Lepage, Dr. Romain Bosc, and Pr. Laurent Lantieri (Centre Hospitalier Universitaire Henri Mondor, Créteil, France), Dr. Henri Mignotte (CRLCC Léon Bérard, Lyon, France), Dr. Joëlle Mollard and Pr. Yves Aubard (Centre Hospitalier Universitaire, Limoges, France), Pr Philippe Rouanet (CRLC Val d’Aurelle, Montpellier, France), Dr. Jacques Saglier (Clinique Saint Jean de Dieu, Paris, France), Pr. Serge Uzan (Hôpital Tenon, Paris, France), Dr. Jean-Luc Verhaeghe (CLCC Alexis Vautrin, Nancy, France), and Pr. Richard Villet (Hôpital des Diaconesses, Paris, France). The authors also thank Dr. Caroline Charles for her invaluable help and efficiency in assisting with the statistical analyses and the writing of the manuscript. Funding for editorial support was provided by LifeCell Corp. The opinions expressed in this article are those of the authors. The authors received no honoraria or fee for service or other form of financial support related to the development of this article.

Disclosure

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Author information

Authors and Affiliations

  1. The Paris Breast Center – L’Institut du Sein, Paris, France

    Krishna B. Clough MD, Victor Acosta-Marín MD, MSc & Claude Nos MD

  2. Centro Clínico de Estereotaxia-CECLINES, Caracas, Venezuela

    Victor Acosta-Marín MD, MSc

  3. CLCC Institut Curie, Paris, France

    Séverine Alran MD

  4. CRLCC Val d’Aurelle, Montpellier, France

    Philippe Rouanet MD, PhD

  5. CLCC Gustave Roussy, Villejuif, France

    Jean-Rémi Garbay MD

  6. CRLCC Oscar Lambret, Lille, France

    Sylvia Giard MD, PhD

  7. CLCC Alexis Vautrin, Nancy, France

    Jean-Luc Verhaeghe MD

  8. CLCC Paoli-Calmettes, Marseille, France

    Gilles Houvenaeghel MD

  9. CLCC Antoine Lacassagne, Nice, France

    Bernard Flipo MD

  10. CLCC Jean Perrin, Clermont-Ferrand, France

    Jacques Dauplat MD, PhD

  11. Polyclinique Courlancy, Reims, France

    Pierre Hervé Dorangeon MD

  12. CLCC René Gauducheau, Nantes, France

    Jean-Marc Classe MD, PhD

  13. Hôpital Tenon, Paris, France

    Roman Rouzier MD, PhD

  14. Hôpital Privé Beauregard, Marseille, France

    Pascal Bonnier MD, PhD

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  1. Krishna B. Clough MD
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  2. Victor Acosta-Marín MD, MSc
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  3. Claude Nos MD
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  8. Jean-Luc Verhaeghe MD
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  12. Pierre Hervé Dorangeon MD
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  14. Roman Rouzier MD, PhD
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  15. Pascal Bonnier MD, PhD
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Corresponding author

Correspondence to Krishna B. Clough MD.

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Breast-conserving surgery (BCS) rates at all centers. (EPS 505 kb)

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Clough, K.B., Acosta-Marín, V., Nos, C. et al. Rates of Neoadjuvant Chemotherapy and Oncoplastic Surgery for Breast Cancer Surgery: A French National Survey. Ann Surg Oncol 22, 3504–3511 (2015). https://doi.org/10.1245/s10434-015-4378-6

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  • DOI: https://doi.org/10.1245/s10434-015-4378-6

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