Radiation-Associated Angiosarcoma After Breast Cancer: High Recurrence Rate and Poor Survival Despite Surgical Treatment with R0 Resection

Table 1 Treatment and outcome for primary angiosarcoma disease

P	Primary operation	Reconstruction	Margins	(neo-) adjuvant treatment	Local recurrence	Metastasis
1	Mastectomy	STSG	R0	No	Yes	No
2	Mastectomy	STSG	R0^a	No	Yes	No
3	Mastectomy	STSG	R0	No	No	Yes
4	Mastectomy	No	R0	No	No	No
5	Mastectomy	No	R0	No	No	No
6	Mastectomy	STSG	R0^a	No	Yes	Yes
7	Mastectomy	No	R0	No	No	Yes
8	Mastectomy	STSG	R0	No	Yes	No
9	Mastectomy	No	R0	No	Yes	No
10	Local excision	No	R0^a	No	Yes	No
11	Mastectomy	No	R0	No	No	No
12	Mastectomy	STSG	R0	No	Yes	Yes
13	Mastectomy	No	R0^a	Radiotherapy	Yes	No
14	Local excision	STSG	R0	No	No	No
15	Mastectomy	Muscle flap	R2	Chemotherapy	Yes	Yes
16	Local excision	No	R0^a	No	No	No
17	Mastectomy	STSG	R2	No	Yes	Yes
18	Mastectomy	No	R2	No	Yes	No
19	Local excision	STSG	R2	No	No	Yes
20	Local excision	No	R0	No	Yes	No
21	Mastectomy	STSG	R1	No	Yes	No
22	Mastectomy	No	R0	No	Yes	Yes
23	Mastectomy	No	R2	No	Yes	Yes
24	Mastectomy	No	R0	No	Yes	No
25	Mastectomy	STSG	R0	No	No	Yes
26	Mastectomy	STSG	R2	No	Yes	Yes
27	Mastectomy	STSG	R0	No	Yes	Yes
28	Mastectomy	No	R0	No	No	No
29	Mastectomy	Muscle flap + STSG	R0^a	No	No	No
30	Local excision	No	R2	No	Yes	Yes
31	Local excision	Muscle flap + STSG	R0^a	No	No	No