References
Chen Y, Kingham K, Ford JM, et al. A prospective study of total gastrectomy for CDH1-positive hereditary diffuse gastric cancer. Ann Surg Oncol. 2011 [Epub ahead of print]. doi:10.1245/s10434-011-1648-9.
Ziogas D, Roukos DH. CDH1 testing: can it predict the prophylactic or therapeutic nature of total gastrectomy in hereditary diffuse gastric cancer? Ann Surg Oncol. 2009;16:2678–81.
Pandalai PK, Lauwers GY, Chung DC, Patel D, Yoon SS. Prophylactic total gastrectomy for individuals with germline CDH1 mutation. Surgery. 2011;149:347–55.
Hackenson D, Edelman DA, McGuire T, Weaver DW, Webber JD. Prophylactic laparoscopic gastrectomy for hereditary diffuse gastric cancer: a case series in a single family. JSLS. 2010;14:348–52.
Garzon R, Marcucci G, Croce CM. Targeting microRNAs in cancer: rationale, strategies and challenges. Nat Rev Drug Discov. 2010;9:775–89.
Roukos DH. Cancer genome explosion and systems biology: Impact on surgical oncology? Ann Surg Oncol. 2011;18(1):12–5.
Roukos DH, Ziogas D. From tumor size and HER2 status to systems oncology for very early breast cancer treatment. Expert Rev Anticancer Ther. 2010;10(2):123–8.
Roukos DH. Isolated tumor cells in breast cancer. N Engl J Med. 2009;361:1994–5; author reply 1995–6.
Roukos DH. Bionetworks-based personalized medicine versus comparative-effectiveness research or harmonization of both in cancer management? Expert Rev Mol Diagn. 2010;10(3):247–50.
Conflict of interest
The authors declare no conflict of interest.
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Liakakos, T. Evidence Expands Total Gastrectomy Decision for Asymptomatic Patients with CDH1 Inherited Mutations. Ann Surg Oncol 18 (Suppl 3), 206–207 (2011). https://doi.org/10.1245/s10434-011-1837-6
Received:
Published:
Issue Date:
DOI: https://doi.org/10.1245/s10434-011-1837-6