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In Reply: Local Excision as an Optional Tool to Individualize Treatment of Rectal Cancer

  • Gastrointestinal Oncology
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Annals of Surgical Oncology Aims and scope Submit manuscript

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References

  1. Ziogas D, Tsekeris P, Fatourou E. Benefits, limitations, and harm of local excision for rectal cancer. Ann Surg Oncol 2008 Mar 18; [Epub ahead of print]

  2. Benson AB III. New approaches to assessing and treating early-stage colon and rectal cancers: cooperative group strategies for assessing optimal approaches in early-stage disease. Clin Cancer Res 2007;13:6913–20

    Article  Google Scholar 

  3. Collette L, Bosset JF, den Dulk M, et al. Patients with curative resection of cT3-4 rectal cancer after preoperative radiotherapy or radiochemotherapy: does anybody benefit from adjuvant fluorouracil-based chemotherapy? A trial of the European Organisation for Research and Treatment of Cancer Radiation Oncology Group. J Clin Oncol 2007;25:4379–86

    Article  PubMed  CAS  Google Scholar 

  4. Machiels JP, Sempoux C, Scalliet P, et al. Phase I/II study of preoperative cetuximab, capecitabine, and external beam radiotherapy in patients with rectal cancer. Ann Oncol 2007;18:738–44

    Article  PubMed  Google Scholar 

  5. Rödel C, Arnold D, Hipp M, et al. Phase I-II trial of cetuximab, capecitabine, oxaliplatin, and radiotherapy as preoperative treatment in rectal cancer. Int J Radiat Oncol Biol Phys 2008;70:1081–6

    PubMed  Google Scholar 

  6. Luna-Pérez P, Segura J, Alvarado I, et al. Specific c-K-ras gene mutations as a tumor-response marker in locally advanced rectal cancer treated with preoperative chemoradiotherapy. Ann Surg Oncol 2000;7:727–31

    Article  PubMed  Google Scholar 

  7. Pan ZZ, Wan DS, Chen G, et al. Co-mutation of p53, K-ras genes and accumulation of p53 protein and its correlation to clinicopathological features in rectal cancer. World J Gastroenterol 2004;10:3688–90

    PubMed  CAS  Google Scholar 

  8. Zlobec I, Vuong T, Compton CC, et al. Combined analysis of VEGF and EGFR predicts complete tumour response in rectal cancer treated with preoperative radiotherapy. Br J Cancer 2008;98:450–6

    Article  PubMed  CAS  Google Scholar 

  9. Rödel F, Frey B, Leitmann W, et al. Survivin antisense oligonucleotides effectively radiosensitize colorectal cancer cells in both tissue culture and murine xenograft models. Int J Radiat Oncol Biol Phys 2008;71:247–55

    PubMed  Google Scholar 

  10. Tsamandas AC, Kardamakis D, Petsas T, et al. Bcl-2, bax and p53 expression in rectal adenocarcinoma. Correlation with classic pathologic prognostic factors and patients’ outcome. In Vivo 2007;21:113–8

    PubMed  CAS  Google Scholar 

  11. Guillem JG, Díaz-González JA, Minsky BD, et al. cT3N0 rectal cancer: potential overtreatment with preoperative chemoradiotherapy is warranted. J Clin Oncol 2008;26:368–73

    Article  PubMed  Google Scholar 

  12. Borschitz T, Wachtlin D, Möhler M, et al. Neoadjuvant chemoradiation and local excision for T2-3 rectal cancer. Ann Surg Oncol 2008;15:712–20

    Article  PubMed  Google Scholar 

  13. Bujko K, Nowacki MP, Nasierowska-Guttmejer A, et al. Prediction of mesorectal nodal metastases after chemoradiation for rectal cancer: results of a randomised trial: implication for subsequent local excision. Radiother Oncol 2005;76:234–40

    Article  PubMed  Google Scholar 

  14. Habr-Gama A, Perez RO, Proscurshim I, et al. Absence of lymph nodes in the resected specimen after radical surgery for distal rectal cancer and neoadjuvant chemoradiation therapy: what does it mean? Dis Colon Rectum 2008;51:277–83

    Article  PubMed  Google Scholar 

  15. Tulchinsky H, Rabau M, Shacham-Shemueli E, et al. Can rectal cancers with pathologic T0 after neoadjuvant chemoradiation (ypT0) be treated by transanal excision alone?. Ann Surg Oncol 2006;13:347–52

    Article  PubMed  Google Scholar 

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Authors and Affiliations

  1. Johannes Gutenberg-University Hospital, Rheinland-Pfalz, Germany

    Thomas Borschitz MD

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  1. Thomas Borschitz MD
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Correspondence to Thomas Borschitz MD.

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Borschitz, T. In Reply: Local Excision as an Optional Tool to Individualize Treatment of Rectal Cancer. Ann Surg Oncol 15, 2630–2631 (2008). https://doi.org/10.1245/s10434-008-9979-x

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  • DOI: https://doi.org/10.1245/s10434-008-9979-x

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