ASO Author Reflections: To Dissect or Not to Dissect—The Clinical Implications of Microscopic Extracapsular Extension in the Sentinel Node

  • Andrea V. BarrioEmail author
  • Monica Morrow
ASO Author Reflections



Dr. Andrea V. Barrio has received speaking honoraria from Roche. Dr. Monica Morrow has received speaking honoraria from Genomic Health and Roche.


  1. 1.
    Giuliano AE, Hunt KK, Ballman KV, et al. Axillary dissection vs no axillary dissection in women with invasive breast cancer and sentinel node metastasis: a randomized clinical trial. JAMA. 2011;305(6):569–75.CrossRefGoogle Scholar
  2. 2.
    Donker M, van Tienhoven G, Straver ME, et al. Radiotherapy or surgery of the axilla after a positive sentinel node in breast cancer (EORTC 10981-22023 AMAROS): a randomised, multicentre, open-label, phase 3 non-inferiority trial. Lancet Oncol. 2014;15(12):1303–10.CrossRefGoogle Scholar
  3. 3.
    Gooch J, King TA, Eaton A, et al. The extent of extracapsular extension may influence the need for axillary lymph node dissection in patients with T1-T2 breast cancer. Ann Surg Oncol. 2014;21(9):2897–903.CrossRefGoogle Scholar
  4. 4.
    Barrio AV, Downs-Canner S, Edelweiss M, et al. Microscopic extracapsular extension in sentinel lymph nodes does not mandate axillary dissection in z0011-eligible patients. Ann Surg Oncol. 2019.

Copyright information

© Society of Surgical Oncology 2020

Authors and Affiliations

  1. 1.Department of SurgeryMemorial Sloan Kettering Cancer CenterNew YorkUSA

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