Advertisement

Annals of Surgical Oncology

, Volume 26, Supplement 3, pp 851–852 | Cite as

ASO Author Reflections: The Prognostic Role of Exosomal PD-L1 in Patients with Gastric Cancer

  • Yibo Fan
  • Yunpeng LiuEmail author
  • Xiujuan Qu
ASO Author Reflections
  • 38 Downloads

Notes

Disclosures

The authors have no conflicts of interest to disclose.

References

  1. 1.
    Eto S, Yoshikawa K, Nishi M, et al. Programmed cell death protein 1 expression is an independent prognostic factor in gastric cancer after curative resection. Gastric Cancer. 2016; 19(2):466–71.CrossRefGoogle Scholar
  2. 2.
    Kim JW, Nam KH, Ahn SH, et al. Prognostic implications of immunosuppressive protein expression in tumors as well as immune cell infiltration within the tumor microenvironment in gastric cancer. Gastric Cancer. 2016; 19(1): 42–52.CrossRefGoogle Scholar
  3. 3.
    Frigola X, Inman BA, Lohse CM, et al. Identification of a soluble form of B7-H1 that retains immunosuppressive activity and is associated with aggressive renal cell carcinoma. Clin Cancer Res. 2011; 17(7): 1915–23.CrossRefGoogle Scholar
  4. 4.
    Theodoraki MN, Yerneni SS, Hoffmann TK, et al. Clinical significance of PD-L1 + exosomes in plasma of head and neck cancer patients. Clin Cancer Res. 2018; 24(4):896–905.CrossRefGoogle Scholar
  5. 5.
    Fan Y, Che X, Qu J, et al. Exosomal PD-L1 retains immunosuppressive activity and is associated with gastric cancer prognosis. Ann Surg Oncol. 2019.  https://doi.org/10.1245/s10434-019-07431-7.CrossRefPubMedGoogle Scholar
  6. 6.
    Chen G, Huang AC, Zhang W, et al. Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response. Nature. 2018; 560(7718):382–86.CrossRefGoogle Scholar

Copyright information

© Society of Surgical Oncology 2019

Authors and Affiliations

  1. 1.Department of Medical OncologyThe First Hospital of China Medical UniversityShenyangChina
  2. 2.Key Laboratory of Anticancer Drugs and Biotherapy of Liaoning ProvinceThe First Hospital of China Medical UniversityShenyangChina

Personalised recommendations