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Long-Term Outcomes of Robot-Assisted Surgery in Patients with Colorectal Cancer

  • Colorectal Cancer
  • Published:
Annals of Surgical Oncology Aims and scope Submit manuscript

Abstract

Background

Robotic technology has been proven to be a safe alternative to conventional laparoscopy with regards to the peri- and postoperative clinical outcomes. Oncological outcomes have been scarcely examined. The purpose of this study was to examine the disease-free survival in relation to the two surgical approaches: robot-assisted surgery and conventional laparoscopy. In addition, all-cause mortality and recurrence-free survival were investigated.

Methods

Between January 2010 and December 2015, patients, undergoing either laparoscopic or robot-assisted elective, curative-intended surgery for colorectal cancer were included.

Results

A total of 9184 patients underwent surgery in the study period: 5978 patients for colon cancer and 3206 patients for rectal cancer. Among patients with colon cancer, 331 patients (5.5%) underwent robot-assisted surgery, and 449 patients (14.0%) underwent robot-assisted surgery in the rectal cancer group. In the adjusted analyses, the hazard ratio (HR) for disease-free survival, for patients with colon cancer was 0.91 [95% confidence interval (CI) 0.71–1.18]. For patients with rectal cancer, the adjusted HR was 0.83 (95% CI 0.65–1.06). No difference in all-cause mortality and recurrence-free survival were observed.

Conclusions

The study demonstrated comparable rates of disease-free survival, all-cause mortality, and recurrence-free survival when comparing robot-assisted surgery with conventional laparoscopy in patients with colorectal cancer.

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Acknowledgment

The work was supported by an unlimited grant from Intuitive Surgical Inc. The company had no influence on the design or conduct of the study, collection, management, analysis or interpretation of the data or preparation, review, or approval of the manuscript. I. Gögenur received an unrestricted research grant from Intuitive and travel grant for advisory board meeting.

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Authors and Affiliations

  1. Department of Surgery, Zealand University Hospital, Køge, Denmark

    Ismail Pinar MD, Tina Fransgaard MD & Ismail Gögenur DMSc

  2. National Institute of Public Health, University of Southern Denmark, Copenhagen, Denmark

    Lau C. Thygesen PhD

  3. Institute for Clinical Medicine, Copenhagen University and Danish Colorectal Cancer Group, Copenhagen, Denmark

    Ismail Gögenur DMSc

Authors
  1. Ismail Pinar MD
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  2. Tina Fransgaard MD
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  3. Lau C. Thygesen PhD
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  4. Ismail Gögenur DMSc
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Correspondence to Ismail Pinar MD.

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Pinar, I., Fransgaard, T., Thygesen, L.C. et al. Long-Term Outcomes of Robot-Assisted Surgery in Patients with Colorectal Cancer. Ann Surg Oncol 25, 3906–3912 (2018). https://doi.org/10.1245/s10434-018-6862-2

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  • DOI: https://doi.org/10.1245/s10434-018-6862-2

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