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Robotic Versus Laparoscopic Right Colectomy with Complete Mesocolic Excision for the Treatment of Colon Cancer: Perioperative Outcomes and 5-Year Survival in a Consecutive Series of 202 Patients

  • Giuseppe Spinoglio
  • Paolo P. Bianchi
  • Alessandra Marano
  • Fabio Priora
  • Luca M. Lenti
  • Ferruccio Ravazzoni
  • Wanda Petz
  • Simona Borin
  • Dario Ribero
  • Giampaolo Formisano
  • Emilio Bertani
Colorectal Cancer
  • 13 Downloads

Abstract

Background

During the past decade, the concept of complete mesocolic excision (CME) has emerged as a possible strategy to minimize recurrence for right colon cancers. The purpose of this study was to compare robotic versus laparoscopic CME in performing right colectomy for cancer.

Methods

Pertinent data of all patients who underwent robotic or laparoscopic right colectomy with CME using a Pfannenstiel incision and intracorporeal anastomosis performed between October 2005 and November 2015 were entered in a prospectively maintained database.

Results

A total of 202 patients underwent robotic (n = 101) or laparoscopic (n = 101) right colectomy within the study period. Patient characteristics were equivalent between groups. The robotic group showed a statistically significant reduction in conversion rate (0% vs. 6.9%, p = 0.01) but a longer operative time (279 min vs. 236 min, p < 0.001) compared with the laparoscopic group. There were no other differences in perioperative clinical or pathological outcomes. Five-years overall survival was 77 versus 73 months for the robotic versus laparoscopic groups (p = 0.64). The disease-free survival (DFS) rates were 85% and 83% for the robotic versus laparoscopic groups (p = 0.58). Among UICC stage III patients, there was a slight but not significant difference in 5-year DFS for the robotic group (81 vs. 68 months; p = 0.122).

Conclusions

Both approaches for right colectomy with CME were safe and feasible and resulted in excellent survival. Robotic assistance was beneficial for performing intracorporeal anastomosis and dissection as evidenced by the lower conversion rates. Further robotic experience may shorten the operative time.

Notes

Acknowledgment

The authors thank Dr. Carlo Di Pietrantonj (Senior Statistician, Regional Epidemiology Unit SeREMI, Local Health Unit, Alessandria, Italy) for his help with the statistical support.

Conflicts of interest and Source of Funding

Dr. Giuseppe Spinoglio is a proctor and speaker for Intuitive Surgical Inc. and he received a grant from Intuitive Surgical Inc. for a study outside the submitted work titled “Sentinel lymph node identification in colon cancer with robotic near-infrared (NIR) fluorescent imaging system.” Drs. Fabio Priora and Luca Matteo Lenti are proctors to Intuitive Surgical, Inc. For the remaining authors, no conflicts of interest were declared.

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Copyright information

© Society of Surgical Oncology 2018

Authors and Affiliations

  • Giuseppe Spinoglio
    • 1
  • Paolo P. Bianchi
    • 2
  • Alessandra Marano
    • 3
  • Fabio Priora
    • 3
  • Luca M. Lenti
    • 3
  • Ferruccio Ravazzoni
    • 3
  • Wanda Petz
    • 1
  • Simona Borin
    • 1
  • Dario Ribero
    • 4
  • Giampaolo Formisano
    • 2
  • Emilio Bertani
    • 1
  1. 1.Division of Gastrointestinal SurgeryEuropean Institute of OncologyMilanItaly
  2. 2.Department of SurgeryMisericordia HospitalGrossetoItaly
  3. 3.Department of General and Oncologic SurgerySS Antonio and Biagio HospitalAlessandriaItaly
  4. 4.Department of SurgeryCandiolo Cancer InstituteTurinItaly

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