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Annals of Surgical Oncology

, Volume 25, Issue 12, pp 3572–3579 | Cite as

Robotic Versus Laparoscopic Total Mesorectal Excision for Sphincter-Saving Surgery: Results of a Single-Center Series of 400 Consecutive Patients and Perspectives

  • Philippe Rouanet
  • Martin Marie Bertrand
  • Marta Jarlier
  • Anne Mourregot
  • Drissa Traore
  • Christophe Taoum
  • Hélène de Forges
  • Pierre-Emmanuel Colombo
Colorectal Cancer

Abstract

Objective

The aim of this study is to compare robotic total mesorectal excision (R-TME) with laparoscopic TME (L-TME) in a series of consecutive rectal cancer patients.

Background

R-TME and L-TME have drawn contradictory reports. A recent phase III trial (ROLARR) concluded that R-TME performed by surgeons with varying experience did not confer an advantage in rectal cancer resection.

Patients and Methods

In this retrospective single-center cohort study (8/2008 to 4/2015), data were prospectively registered. A total of 200 L-TME and 200 R-TME were operated consecutively without selection. The primary outcome was the conversion rate to open laparotomy or transanal TME. The secondary endpoints were type of anastomosis, operative time, postoperative morbidity, circumferential radial (CRM) and distal margins, quality of life, bladder and sexual dysfunction, and oncological outcomes.

Results

Baseline characteristics were well balanced. Type of anastomosis [colo-anal anastomosis (CAA) 40% vs 49%; p < 0.001], transanal TME (5% vs 13%; p = 0.005), and conversion rate (2% vs 9.5%; odd ratio (OR): 0.19 [95% confidence interval (CI): 0.05–0.60]) were significantly different. Intersphincteric resection (39% vs 47%), diverting stoma (66.5% vs 68%), CRM involvement, median operative time (243 vs 232 min), and R0 resection rate were similar. Conversion risk was lower for R-TME in male patients and those with small tumors (< 5 cm). The 3-year overall survival rate was 84.1% [77.3–88.9%] and 88.4% [82.9–92.2%] in the R-TME and L-TME group. No significant differences were reported in quality of life, and urinary or sexual function.

Conclusions

R-TME is less likely to be converted to open surgery than L-TME; operative time and curative pathologic criteria are equivalent. Future prospective trial should compare standardized procedures performed by experienced surgeons for subgroups of high-risk patients.

Notes

Acknowledgements

The authors thank Drs. Mathias Alline, Julien Coget, and Fabien Wilk for participating in the study and surgical assistance. The authors also thank Nabila Bouazza for valuable help regarding data collection and management of the database and the project, and Sylvain Boudon for data management.

Disclosure

PR is proctor for Intuitive Surgical Inc. All other authors have nothing to disclose regarding the present study.

Supplementary material

10434_2018_6738_MOESM1_ESM.docx (77 kb)
Supplementary material 1 (DOCX 77 kb)
10434_2018_6738_MOESM2_ESM.docx (128 kb)
Supplementary material 2 (DOCX 127 kb)

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Copyright information

© Society of Surgical Oncology 2018

Authors and Affiliations

  • Philippe Rouanet
    • 1
  • Martin Marie Bertrand
    • 1
  • Marta Jarlier
    • 2
  • Anne Mourregot
    • 1
  • Drissa Traore
    • 1
  • Christophe Taoum
    • 1
  • Hélène de Forges
    • 3
  • Pierre-Emmanuel Colombo
    • 1
  1. 1.Surgical Oncology DepartmentInstitut du Cancer de Montpellier (ICM), Univ MontpellierMontpellierFrance
  2. 2.Biometrics UnitInstitut du Cancer de Montpellier (ICM), Univ MontpellierMontpellierFrance
  3. 3.Clinical Research UnitInstitut du Cancer de Montpellier (ICM), Univ MontpellierMontpellierFrance

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