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Annals of Surgical Oncology

, Volume 24, Issue 9, pp 2595–2595 | Cite as

Total Laparoscopic Management for Stage IV Colorectal Cancer Requiring Multivisceral Resection

  • Y. Nancy You
  • Hironori Shiozaki
  • Jeffrey E. Lee
  • Guillaume Passot
  • Claire Goumard
  • Masayuki Okuno
  • Thomas A. Aloia
  • Cathy Eng
  • George Chang
  • Jean-Nicolas Vauthey
  • Claudius ConradEmail author
Colorectal Cancer

Abstract

Background

Surgical resection of all sites of disease, in combination with effective systemic chemotherapy, offers the only potential chance for cure for patients with stage IV colorectal cancer (CRC). Coordinated multistage resection using a minimally invasive approach may provide optimal oncologic outcome while potentially offering the benefit of decreased morbidity.

Patient

A 66-year-old women presented with transverse colon cancer and synchronous metastasis (CRLM) in segment IV involving the middle hepatic vein and main left portal pedicle, as well as the left adrenal gland. Due to favorable response to neoadjuvant chemotherapy (FOLFOX/bevacizumab), the patient was considered for resection but developed some obstructive symptoms from the primary tumor, necessitating re-coordination of treatment sequencing from the ‘liver-first’ approach.

Methods

The first procedure combined laparoscopic subtotal colectomy (extracorporeal anastomosis) with left adrenalectomy. After restaging, CRLM was removed separately 2 months later via laparoscopic left hepatectomy extending beyond the middle hepatic vein. Successful completion of the two procedures depended on optimal patient/port positioning for the combined colon/adrenal surgery and the second-stage liver resection. Postoperative lengths of stay were 4 and 3 days, respectively, and were without complication. Adjuvant FOLFOX was initiated 21 days following liver surgery, and the patient has been disease-free for 36 months.

Conclusion

This case illustrates the feasibility of the total laparoscopic approach to multivisceral resection for synchronous stage IV CRC in the context of a preplanned, staged multidisciplinary strategy. This approach may offer optimal cancer management, including early return to systemic therapy, shortened time intervals between stages, and minimal postoperative morbidity.1 3

Notes

DISCLOSURE

Y. Nancy You, Hironori Shiozaki, Jeffrey E. Lee, Guillaume Passot, Claire Goumard, Masayuki Okuno, Thomas A. Aloia, Cathy Eng, George Chang, Jean-Nicolas Vauthey, and Claudius Conrad have declared no conflicts of interest.

Supplementary material

Supplementary material 1 (MP4 275952 kb)

REFERENCES

  1. 1.
    Conrad C, Gayet B (eds). Laparoscopic liver, pancreas, and biliary surgery: textbook and illustrated video atlas. Wiley-Blackwell, Chichester; 2017.Google Scholar
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    Yamashita S, Sheth RA, Niekamp AS, Aloia TA, Chun YS, Lee JE, et’al. Comprehensive complication index predicts cancer-specific survival after resection of colorectal metastases independent of RAS mutational status. Ann Surg. Epub 4 Oct 2016.Google Scholar
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    Mise Y, Aloia TA, Brudvik KW, Schwarz L, Vauthey JN, Conrad C. Parenchymal-sparing hepatectomy in colorectal liver metastasis improves salvageability and survival. Ann Surg. 2016;263(1):146–52.CrossRefPubMedGoogle Scholar

Copyright information

© Society of Surgical Oncology 2017

Authors and Affiliations

  • Y. Nancy You
    • 1
  • Hironori Shiozaki
    • 1
  • Jeffrey E. Lee
    • 1
  • Guillaume Passot
    • 1
  • Claire Goumard
    • 1
  • Masayuki Okuno
    • 1
  • Thomas A. Aloia
    • 1
  • Cathy Eng
    • 1
  • George Chang
    • 1
  • Jean-Nicolas Vauthey
    • 1
  • Claudius Conrad
    • 1
    • 2
    Email author
  1. 1.Department of Surgical OncologyThe University of Texas MD Anderson Cancer CenterHoustonUSA
  2. 2.Department of Surgical OncologyHepato-Pancreato-Biliary SurgeryHoustonUSA

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