Annals of Surgical Oncology

, Volume 22, Issue 11, pp 3590–3596 | Cite as

Laparoscopic Versus Open Gastrectomy for Gastric Adenocarcinoma in the West: A Case–Control Study

  • Kaitlyn J. Kelly
  • Luke Selby
  • Joanne F. Chou
  • Katerina Dukleska
  • Marinela Capanu
  • Daniel G. Coit
  • Murray F. Brennan
  • Vivian E. StrongEmail author
Gastrointestinal Oncology



Data on laparoscopic gastrectomy in patients with gastric cancer in the Western hemisphere are lacking. This study aimed to compare outcomes following laparoscopic versus open gastrectomy for gastric adenocarcinoma at a Western center.


Eighty-seven consecutive patients who underwent laparoscopic gastrectomy from November 2005 to April 2013 were compared with 87 patients undergoing open resection during the same time period. Patients were matched for age, stage, body mass index, and procedure (distal subtotal vs. total gastrectomy). Endpoints were short- and long-term perioperative outcomes.


Overall, 65 patients (37 %) had locally advanced disease, and 40 (23 %) had proximal tumors. The laparoscopic approach was associated with longer operative time (median 240 vs.165 min; p < 0.01), less blood loss (100 vs.150 mL; p < 0.01), higher rate of microscopic margin positivity (9 vs.1 %; p = 0.04), decreased duration of narcotic and epidural use (2 vs. 4 days, p = 0.04, and 3 vs. 4 days, p = 0.02, respectively), decreased minor complications in the early (27 vs. 16 %) and late (17 vs. 7 %) postoperative periods (p < 0.01), decreased length of stay (5 vs. 7 days; p = 0.01), and increased likelihood of receiving adjuvant therapy (82 vs. 51 %; p < 0.01). There was no difference in the number of lymph nodes retrieved (median 20 in both groups), major morbidity, or 30-day mortality.


Laparoscopic gastrectomy for gastric adenocarcinoma is safe and effective for select patients in the West.


Gastric Cancer Total Gastrectomy Gastric Adenocarcinoma Laparoscopic Group Laparoscopic Gastrectomy 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Society of Surgical Oncology 2015

Authors and Affiliations

  • Kaitlyn J. Kelly
    • 1
  • Luke Selby
    • 1
  • Joanne F. Chou
    • 2
  • Katerina Dukleska
    • 1
  • Marinela Capanu
    • 2
  • Daniel G. Coit
    • 1
  • Murray F. Brennan
    • 1
  • Vivian E. Strong
    • 1
    Email author
  1. 1.Department of SurgeryMemorial Sloan-Kettering Cancer CenterNew YorkUSA
  2. 2.Department of Epidemiology and BiostatisticsMemorial Sloan-Kettering Cancer CenterNew YorkUSA

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