Annals of Surgical Oncology

, Volume 16, Issue 8, pp 2264–2269 | Cite as

Management of Intraductal Papillomas of the Breast: An Analysis of 129 Cases and Their Outcome

  • Nasim Ahmadiyeh
  • Mariana A. Stoleru
  • Sughra Raza
  • Susan C. Lester
  • Mehra Golshan
Breast Oncology

Abstract

Introduction

The management of intraductal papillomas of the breast has been controversial; some advocate surgical excision of all lesions despite benign pathologic features, whereas others excise only those specimens with atypia.

Methods

We conducted a retrospective review of 129 core-biopsy-proven papillomas of the breast with atypia (n = 43) and without atypia (n = 86) and determined the rate of missed carcinoma in surgically excised specimen in each group.

Results

Carcinoma was found in 22.5% of the surgically excised specimens in the atypia group (9/40) and in 3% of the surgically excised specimens in the no atypia group (1/29).

Conclusions

Our findings confirm the practice that papillomas with atypical features should be excised, and suggest that in patients with adequate follow-up, benign papillomas may be managed conservatively.

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Copyright information

© Society of Surgical Oncology 2009

Authors and Affiliations

  • Nasim Ahmadiyeh
    • 1
  • Mariana A. Stoleru
    • 2
  • Sughra Raza
    • 3
  • Susan C. Lester
    • 2
  • Mehra Golshan
    • 1
  1. 1.Department of SurgeryBrigham and Women’s Hospital and the Dana Farber Cancer InstituteBostonUSA
  2. 2.Department of PathologyBrigham and Women’s HospitalBostonUSA
  3. 3.Department of RadiologyBrigham and Women’s HospitalBostonUSA

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