Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy in the Management of Peritoneal Surface Malignancies of Colonic Origin: A Consensus Statement
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Surgical resection remains the hallmark therapy for primary colon cancer. It allows the patients to become clinically disease free, provides proper staging, and determines who should receive adjuvant systemic chemotherapy. Treatment options for patients with unresectable metastatic disease have improved significantly in the past few years. A review of the published data in the treatment of patients with stage IV colorectal cancer, outlining the surgical and medical therapeutic options demonstrates that medical management, with combinations of cytotoxic chemotherapy, and/or biological agents, has resulted in an unprecedented median survival>20 months. However, these therapeutic combinations are not an optimal therapeutic strategy for all categories of stage IV disease. Systemic treatment alone is no longer appropriate for patients with limited peritoneal dissemination from a primary or recurrent colon cancer. The surgical management of peritoneal surface malignancies of colonic origin...
KeywordsPeritoneal Carcinomatosis Cytoreductive Surgery Intraperitoneal Chemotherapy Ureteral Obstruction Peritoneal Cancer Index
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