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Annals of Surgical Oncology

, Volume 12, Issue 11, pp 864–865 | Cite as

If at First or Second You Don’t Succeed: Mastectomy?

  • Henry M. KuererEmail author
Editorial

In this issue of Annals of Surgical Oncology, Menses et al.1 reviewed factors associated with local recurrence after breast-conservation surgery in 459 patients treated for invasive and in situ carcinoma of the breast. Overall, the authors reported a local recurrence in 28 patients (6%) at 5 years. Nearly 50% of patients (n = 229) in this series had at least 1 re-excision, and only 22 patients had 2 or more re-excisions. The local recurrence rate in the 22 patients re-excised 2 or more times was 13.4%, compared with 5.6% of patients with 1 re-excision and 3.5% without a re-excision at 5 years. On multivariate analysis, the authors also found, in addition to the number of re-excisions, that age younger than 50 years and omission of radiotherapy were also independent factors associated with an increased local recurrence rate.

The results of this study are intuitive to the surgical oncologist who routinely performs breast-conservation surgery. Many of us will continue to perform multiple...

Keywords

Local Recurrence Local Recurrence Rate Partial Breast Irradiation Conformal Radiation Treatment Local Breast Cancer Recurrence 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

References

  1. 1.
    Menses TS, Tartter PI, Bleiweiss I, et al. The consequence of multiple re-excisions to obtain clear lumpectomy margins in breast cancer patients. Ann Surg Oncol (in press)Google Scholar
  2. 2.
    Tartter PI, Kaplan J, Bleiweiss I, et al. Lumpectomy margins, reexcision, and local recurrence of breast cancer. Am J Surg 2000;2:81–85CrossRefGoogle Scholar
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    Morrow M, Strom EA, Bassett LW, et al. Standard for breast conservation therapy in the management of invasive breast carcinoma. CA Cancer J Clin 2002;52:277–300Google Scholar
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    Chagpar A, Yen T, Sahin A, et al. Intraoperative margin assessment reduces reexcision rates in patients with ductal carcinoma in situ treated with breast-conserving surgery. Am J Surg 2003;4:371–377CrossRefGoogle Scholar
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    Kuerer HM, Julian TB, Strom EA, et al. Accelerated partial breast irradiation after conservative surgery for breast cancer. Ann Surg 2004;3:338–351CrossRefGoogle Scholar
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    Kuerer HM, Arthur DW, Haffty BG. Repeat breast-conserving surgery for in-breast local breast carcinoma recurrence: the potential role of partial breast irradiation. Cancer 2004;11:2269–2280CrossRefGoogle Scholar

Copyright information

© The Society of Surgical Oncology, Inc. 2005

Authors and Affiliations

  1. 1.Department of Surgical OncologyThe University of Texas M. D. Anderson Cancer CenterHouston

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