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The Importance of Dielectric Constant for Drug Solubility Prediction in Binary Solvent Mixtures: Electrolytes and Zwitterions in Water + Ethanol

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Authors and Affiliations

  1. Liver and Gastrointestinal Diseases Research Center, Tabriz University of Medical Sciences, Tabriz, 51664, Iran

    Mohammad Amin Abolghassemi Fakhree

  2. Grupo de Investigaciones Farmacéutico-Fisicoquímicas, Departamento de Farmacia, Facultad de Ciencias, Universidad Nacional de Colombia, A.A. 14490, Bogotá, DC, Colombia

    Daniel R. Delgado & Fleming Martínez

  3. Drug Applied Research Center and Faculty of Pharmacy, Tabriz University of Medical Sciences, Tabriz, 51664, Iran

    Abolghasem Jouyban

Authors
  1. Mohammad Amin Abolghassemi Fakhree
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  2. Daniel R. Delgado
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  3. Fleming Martínez
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  4. Abolghasem Jouyban
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Correspondence to Mohammad Amin Abolghassemi Fakhree.

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Abolghassemi Fakhree, M., Delgado, D.R., Martínez, F. et al. The Importance of Dielectric Constant for Drug Solubility Prediction in Binary Solvent Mixtures: Electrolytes and Zwitterions in Water + Ethanol. AAPS PharmSciTech 11, 1726–1729 (2010). https://doi.org/10.1208/s12249-010-9552-3

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