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In Vivo Predictive Dissolution and Simulation Workshop Report: Facilitating the Development of Oral Drug Formulation and the Prediction of Oral Bioperformance

The AAPS Journal volume 20, Article number: 100 (2018) Cite this article

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Acknowledgments

The authors thank Ms. Kelly Gerstenberg for her invaluable help for this successful workshop.

Funding

This work is financially supported by the American Association of Pharmaceutical Sciences (AAPS).

Author information

Author notes

  1. Yasuhiro Tsume

    Present address: Merck & Co., Inc., 126 E Lincoln Ave, Rahway, New Jersey, 07065, USA

Authors and Affiliations

  1. College of Pharmacy, The University of Michigan, 428 Church Street, Ann Arbor, Michigan, 48109, USA

    Yasuhiro Tsume, Gordon L. Amidon, Duxin Sun & Gregory E. Amidon

  2. Merck & Co., Inc., 126 E Lincoln Ave, Rahway, New Jersey, 07065, USA

    Sanjaykumar Patel

  3. Department of Pharmacy and Pharmacology, University of Bath, Bath, UK

    Nikoletta Fotaki

  4. Department of Pharmacy, Uppsala University, Uppsala, Sweden

    Christel Bergstrӧm

  5. Aerospace Engineering Sciences, University of Colorado, Boulder, Colorado, USA

    James G. Brasseur

  6. Research and Development, Lonza, Bend, Oregon, USA

    Deanna M. Mudie

  7. Universidad Miguel Hernández de Elche, Elche, Spain

    Marival Bermejo

  8. Abbvie, Inc., Chicago, Illinois, USA

    Ping Gao

  9. Merck & Co., Inc., West Point, Pennsylvania, 19486, USA

    Wei Zhu & Andre Hermans

  10. Eli Lilly and Company, Indianapolis, Indiana, 46285, USA

    David C. Sperry

  11. Department of Pharmacy, National and Kapodistrian University of Athens, Athens, Greece

    Maria Vertzoni

  12. F. Hoffmann-La Roche, Ltd., Roche Innovation Center, Basel, Switzerland

    Neil Parrott

  13. Food and Drug Administration, Silver Spring, Maryland, 21201, USA

    Robert Lionberger

  14. Astellas Pharma Inc., Shizuoka, Japan

    Atsushi Kambayashi

  15. Bristol-Myers Squibb Company, New Brunswick, New Jersey, 08903, USA

    Xujin Lu

Authors
  1. Yasuhiro Tsume
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  2. Sanjaykumar Patel
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  3. Nikoletta Fotaki
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  4. Christel Bergstrӧm
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  5. Gordon L. Amidon
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  6. James G. Brasseur
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  7. Deanna M. Mudie
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  8. Duxin Sun
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  9. Marival Bermejo
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  10. Ping Gao
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  11. Wei Zhu
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  12. David C. Sperry
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  13. Maria Vertzoni
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  14. Neil Parrott
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  15. Robert Lionberger
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  16. Atsushi Kambayashi
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  17. Andre Hermans
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  18. Xujin Lu
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  19. Gregory E. Amidon
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Corresponding author

Correspondence to Yasuhiro Tsume.

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Cite this article

Tsume, Y., Patel, S., Fotaki, N. et al. In Vivo Predictive Dissolution and Simulation Workshop Report: Facilitating the Development of Oral Drug Formulation and the Prediction of Oral Bioperformance. AAPS J 20, 100 (2018). https://doi.org/10.1208/s12248-018-0260-3

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  • DOI: https://doi.org/10.1208/s12248-018-0260-3

Key words

  • dissolution
  • formulation prediction
  • in vivo prediction
  • simulation