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Studies on neomycin production using immobilized cells ofS marinensis NUV-5 in various reactor configurations: A technical note

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Conclusion

Stirred tank, fluidized bed, and airlift reactors produced similar neomycin activity with immobilized cells. Packed bed reactor clearly under performed, probably because of insufficient aeration or mixing. Neomycin production using immobilized cells in fermentors requires good mixing and aeration.

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Authors and Affiliations

  1. Pharmaceutical Biotechnology Division, Department of Pharmaceutical Sciences, Andhra University, 530 003, Visakhapatnam, India

    Bandi Srinivasulu, Poluri Ellaiah & Kunamneni Adinarayana

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  1. Bandi Srinivasulu
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  2. Poluri Ellaiah
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  3. Kunamneni Adinarayana
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Correspondence to Poluri Ellaiah.

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Srinivasulu, B., Ellaiah, P. & Adinarayana, K. Studies on neomycin production using immobilized cells ofS marinensis NUV-5 in various reactor configurations: A technical note. AAPS PharmSciTech 4, 46 (2003). https://doi.org/10.1208/pt040346

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  • DOI: https://doi.org/10.1208/pt040346

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