Skip to main content
Log in

Concluding summary: Proceedings of the AAPS Biotec Open Forum on “Aggregation of Protein Therapeutics”

  • Published:
The AAPS Journal Aims and scope Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

References

  1. Rosenberg AS. Effects of protein aggregates. An immunologic perspective. AAPS J. 2006;8:E501-E507.

    Article  PubMed  Google Scholar 

  2. Chi EY, Weickman J, Carpenter JF, Manning MC, Randolph TW. Heterogeneous nucleation-controlled particulate formation of recombinant human platelet-activating factor acetylhydrolase in pharmaceutical formulation. J Pharm Sci. 2005;94:256–274.

    Article  PubMed  CAS  Google Scholar 

  3. Cromwell MEM, Hilario E, Jacobson F. Protein aggregation and bioprocessing. AAPS J. 2006;8:E572-E579.

    Article  PubMed  CAS  Google Scholar 

  4. Philo JS. Is any measurement method optimal for all aggregate sizes and types? AAPS J. 2006;8:E564-E571.

    Article  PubMed  CAS  Google Scholar 

  5. Berkowitz SA. Role of analytical ultracentrifugation in assessing the aggregation of protein biopharmaceuticals. AAPS J. 2006;8:E590-E605.

    Article  PubMed  CAS  Google Scholar 

  6. Schuck P. Size-distribution analysis of macromolecules by sedimentation velocity ultracentrifugation and lamm equation modeling. Biophysical Journal. 2000;78:1606–1619.

    Article  PubMed  CAS  Google Scholar 

  7. Liu J, Andya JD, Shire SJ. A critical review of analytical ultracentrifugation and field flow fractionation methods for measuring protein aggregation. AAPS J. 2006;8:E580-E589.

    Article  PubMed  CAS  Google Scholar 

  8. Shire SJ. 2005 AAPS Biotechnology Conference Open Forum on Aggregation of Protein Therapeutics-Panel Discussion, June 5–8, 2005, San Francisco, CA. AAPS J. 2006;8:E644-E654.

    Article  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Additional information

Published: December 1, 2006

Rights and permissions

Reprints and permissions

About this article

Cite this article

Shire, S.J., Cromwell, M. & Liu, J. Concluding summary: Proceedings of the AAPS Biotec Open Forum on “Aggregation of Protein Therapeutics”. AAPS J 8, 82 (2006). https://doi.org/10.1208/aapsj080482

Download citation

  • Received:

  • Accepted:

  • DOI: https://doi.org/10.1208/aapsj080482

Keywords

Navigation