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AAPS PharmSciTech

, Volume 19, Issue 6, pp 2750–2750 | Cite as

RETRACTED ARTICLE: Development and In Vitro-In Vivo Characterization of Chronomodulated Pulsatile Delivery Formulation of Terbutaline Sulphate by Box-Behnken Statistical Design

  • Prabhjot Singh Bajwa
  • Anurag Bhargava
  • Jaya Sharma
  • Shailesh SharmaEmail author
  • Abhimanyu Rai Sharma
  • Binu Sharma
Research Article

This article has been retracted by the journal because the editors have clear evidence that the scientific findings in this article are unreliable. The article describes the formulation and in vitro/in vivo testing of an Optimized Pulsatile Delivery Tablet (OP1) as follows: 10 mm diameter press-coated Pulsatile Delivery Tablet (PDT) that contains a 6 mm diameter Fast-Release Core Tablet (FRCT), prepared, characterized and tested in the rabbit pharmacokinetic study. The authors have confirmed to the editors that they actually prepared and tested a “special batch” of FRCT core tablets having a diameter of 2.5 mm contained in 5 mm press-coated PDT tablets having a diameter of 5 mm, but the use of this smaller FRCT/PDT is not described anywhere in the manuscript. Therefore, the editors believe that since the article does not describe the dosage form that was actually studied, the findings in the article are unreliable. All authors agreed to this retraction. The online version of this article contains the full text of the retracted article as electronic supplementary material.

Supplementary material

12249_2017_838_MOESM1_ESM.pdf (3.6 mb)
ESM 1 Former article version (PDF 3.59 mb)

Copyright information

© American Association of Pharmaceutical Scientists 2017

Authors and Affiliations

  • Prabhjot Singh Bajwa
    • 1
  • Anurag Bhargava
    • 1
  • Jaya Sharma
    • 2
  • Shailesh Sharma
    • 3
    Email author
  • Abhimanyu Rai Sharma
    • 1
  • Binu Sharma
    • 1
  1. 1.Ch. Devilal College of PharmacyYamunanagarIndia
  2. 2.School of Pharmaceutical SciencesJaipur National UniversityJaipurIndia
  3. 3.Department of PharmaceuticsAmar Shaheed Baba Ajit Singh Jujhar Singh Memorial College of PharmacyRoparIndia

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