The effect of marital status on survival in late-stage cancer patients: An analysis based on surveillance, epidemiology, and end results (SEER) data, in the United States

  • Hong LaiEmail author
  • Shenghan Lai
  • Arnon Krongrad
  • Edward Trapido
  • J. Bryan Page
  • Clyde B. McCoy


Recently findings that marital status is associated with survival in patients with late-stage prostate cancer led to an examination of the generalizability of this association for all cancers. We restricted the investigation to patients with late-stage cancer using population-based data collected from 261,070 patients with late-stage cancer at multiple sites in the United States to determine relations between marital status and survival. After controlling for age, race, and treatment, married patients with cancers of all major primary sites had significantly better survival than single, separated, divorced, or widowed patients. Although single and widowed patients had the poorest prognosis in general, single patients appeared to show the most consistently poor survival across the different types of cancers. Survival differences by marital status were more pronounced in men than in women. This observation raises the possibility that some characteristics associated with being married delay death from cancer. These findings require investigators to ask new questions about the effect of being married and its possible correlates, such as general health status, access to health care, and socioeconomic status. Known correlates of marital status, such as available social support and social isolation also merit attention in relation to these findings.

Key words

marital status cancer late stage survival SEER 


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Copyright information

© International Society of Behavioral Medicine 1999

Authors and Affiliations

  • Hong Lai
    • 1
    Email author
  • Shenghan Lai
    • 2
  • Arnon Krongrad
    • 2
  • Edward Trapido
    • 1
  • J. Bryan Page
    • 3
  • Clyde B. McCoy
    • 1
  1. 1.Department of Epidemiology and Public HealthUniversity of Miami School of Medicine, Dominion Tower, Room 1111A (D-93)Miami
  2. 2.Department of MedicineUniversity of Miami School of MedicineMiami
  3. 3.Department of Psychiatry and Behavioral SciencesUniversity of Miami School of MedicineMiami

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