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Association between type a behavior pattern and coronary artery spasm in japanese patients

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Abstract

The relations between the Jenkins Activity Survey (JAS) Type A score and coronary atherosclerosis and spasm were examined in 192 patients (115 men and 77 women) undergoing coronary angiography. Thirty-nine men (34%) and 12 women (16%) had significant (>- 75%) coronary stenosis. In 97 patients (54 men and 43 women) with no significant coronary stenosis, a coronary spasm provocation test by 0.2 to 0.4 mg of ergometrine was performed, by which a significant focal spasm (>- 75% reduction of luminal diameter) was induced in 22 men (40%) and 5 women (12%). Men who showed a significant focal spasm had a higher Type A score than men who showed no such spasm (1.9 ± 8.4 vs. -2.4 ± 8.3, p < 0.05). Discriminant analysis in male patients revealed that the induction of coronary spasm can be predicted by the JAS Type A score and smoking habit (p = 0.04). No such association was found for female patients. These results suggest that the Type A behavior pattern as assessed by the JAS may be associated with coronary spasm in Japanese men without significant coronary stenosis.

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We gratefully acknowledge the scientific advice of Takao Fujinami.

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Hori, R., Suzuki, T. & Hayano, J. Association between type a behavior pattern and coronary artery spasm in japanese patients. Int. J. Behav. Med. 3, 221–232 (1996). https://doi.org/10.1207/s15327558ijbm0303_3

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