Fig. 6

Photomicrographs of sections in the cerebellar cortex immunohistochemically stained with inducible nitric oxide synthase (iNOS) (×400). A and B Negative and positive control groups show a negative reaction in the cerebellar cortex. C The acute treated group shows positive cells mainly in Purkinje cell (thick arrow) and granular cell layers (arrow). D and E Chronic treated and chronic withdrawal groups reveal strong positive reactions in cells of granular (arrow), molecular (arrowhead), and Purkinje cell layers (thick arrow)