|
Variable
|
Tertile 1
|
Tertile 2
|
Tertile 3
|
|---|
|
No. (%)
|
1853 (23.8)
|
–
|
–
|
–
|
|
Leg/total %
|
Unadjusted
|
1.00 (Ref)
|
0.57 (0.47, 0.69)
|
0.35 (0.29, 0.42)
|
|
Model 1
|
1.00 (Ref)
|
0.63 (0.52, 0.78)
|
0.44 (0.36, 0.54)
|
|
Model 2
|
1.00 (Ref)
|
0.79 (0.65, 0.97)
|
0.68 (0.56, 0.82)
|
|
Model 3
|
1.00 (Ref)
|
0.81 (0.66, 0.99)
|
0.70 (0.55, 0.89)
|
|
Leg lean/fat ratio
|
Unadjusted
|
1.00 (Ref)
|
0.83 (0.69, 0.98)
|
0.69 (0.57, 0.83)
|
|
Model 1
|
1.00 (Ref)
|
0.86 (0.73, 1.02)
|
0.74 (0.61, 0.90)
|
|
Model 2
|
1.00 (Ref)
|
1.19 (0.99, 1.43)
|
1.37 (1.07, 1.74)
|
|
Model 3
|
1.00 (Ref)
|
1.11 (0.92, 1.34)
|
1.23 (0.95, 1.60)
|
|
Leg fat %
|
Unadjusted
|
1.00 (Ref)
|
1.24 (1.01, 1.53)
|
1.44 (1.19, 1.73)
|
|
Model 1
|
1.00 (Ref)
|
1.20 (0.97, 1.45)
|
1.38 (1.14, 1.70)
|
|
Model 2
|
1.00 (Ref)
|
0.90 (0.74, 1.11)
|
0.75 (0.59, 0.95)
|
|
Model 3
|
1.00 (Ref)
|
0.93 (0.75, 1.15)
|
0.82 (0.63, 1.05)
|
- Data are presented as odds ratio (95% confidence interval)
- Model 1 adjusts for demographic factors (age, sex, race/ethnicity, poverty index). Model 2 adjusts for Model 1 factors + cardiometabolic factors (systolic blood pressure, heart rate, triglycerides, body mass index, truncal fat mass, high density lipoprotein, alanine aminotransferase, diabetes status, serum creatinine, albuminuria, smoking, alcohol consumption). Model 3 adjusts for other examination factors (leg fat parameters other than main predictor, arm fat parameters other than main predictor). Lean/fat ratio and fat % variables were not included in the same model due to significant correlation and high variance inflation factor. % Total fat in lower extremities corresponds to leg/total %, leg lean mass/fat mass ratio corresponds to leg lean/fat ratio, % fat in total leg mass corresponds to leg fat %. Identical for arm measures. Tertiles are as follows: leg/total % (female: < 36, 36–41%, ≥41%; male: < 31.5, 31.5–36.0%, ≥36%); leg lean/fat ratio (female: < 1.1, 1.1–1.4, ≥1.40; male: < 2.3, 2.3–3.0, ≥3.0); leg fat % (female: < 40, 40–45%, ≥45%; male: < 24, 24–29%, ≥29%)