Table 2 Acne lesion counts in subjects after treatment with EE/CMA or EE/DRSP

From: A comparison of combined oral contraceptives containing chlormadinone acetate versus drospirenone for the treatment of acne and dysmenorrhea: a randomized trial

Testing for Efficacy EE/CMAa (n = 90) EE/DRSPa (n = 90)
Baseline Month 1 Month 3 Month 6 Baseline Month 1 Month 3 Month 6
Mean ± S.D. Mean change from baseline ± S.D. Mean ± S.D. Mean change from baseline ± S.D.
Acne
 Comedones 47.17 ± 22.30 −9.21 ± 1.22 − 23.37 ± 1.67 − 35.00 ± 1.95 42.94 ± 21.08 − 7.02 ± 1.22 − 19.33 ± 1.67 − 28.82 ± 1.95
 Papules 14.60 ± 6.63 − 3.34 ± 0.48 −6.29 ± 0.57 − 9.74 ± 0.63 13.67 ± 5.94 −2.16 ± 0.48 −5.06 ± 0.57 −7.57 ± 0.63
 Pustules/Nodules 3.1 ± 3.59 −0.23 ± 0.35 −1.55 ± 0.40 −2.38 ± 0.47 3.14 ± 4.29 −0.6 ± 0.35 −2.02 ± 0.397 −2.43 ± 0.47
   Total Lesions 64.21 ± 25.09 −12.40 ± 1.35 −30.84 ± 1.75 − 46.78 ± 2.11 59.66 ± 23.44 −9.47 ± 1.35 −26.52 ± 1.75 −38.90 ± 2.11
  1. aContinuous variables are presented as mean ± S.D. Counts show changes month by month within treatment groups