The Kennel Club: Breed Information Centre [http://www.thekennelclub.org.uk/services/public/breed/].
The Kennel Club: Breed Standards Information: Dog Breeds & Groups [http://www.thekennelclub.org.uk/activities/dog-showing/breed-standards/].
The Kennel Club: Breed registration statistics [http://www.thekennelclub.org.uk/registration/breed-registration-statistics/].
Dedola C, Ressel L, Hill PB, Van Den Broek AHM, Thoday KL. Idiopathic generalized sebaceous gland hyperplasia of the border terrier: a morphometric study. Vet Dermatol. 2010;21(5):494–502.
Black V, Garosi L, Lowrie M, Harvey RJ, Gale J. Phenotypic characterisation of canine epileptoid cramping syndrome in the border terrier. J Small Anim Pract. 2014;55(2):102–7.
Kearsley-Fleet L, O'Neill DG, Volk HA, Church DB, Brodbelt DC. Prevalence and risk factors for canine epilepsy of unknown origin in the UK. Vet Rec. 2013;172(13):338.
O'Neill DG, Lee MM, Brodbelt DC, Church DB, Sanchez RF. Corneal ulcerative disease in dogs under primary veterinary care in England: epidemiology and clinical management. Canine Genetics and Epidemiology. 2017;4(1):5.
Holt PE, Hotston Moore A, Thrusfield MV. Breed predisposition to ureteral ectopia in bitches in the UK. Vet Rec. 2000;146(19):561.
O'Neill DG, O'Sullivan AM, Manson EA, Church DB, Boag AK, McGreevy PD, et al.: Canine dystocia in 50 UK first-opinion emergency-care veterinary practices: prevalence and risk factors. Veterinary Record 2017,BIY70055. doi:10.1136/vr.104108(Published Online).
Collins LM, Asher L, Summers JF, Diesel G, McGreevy PD. Welfare epidemiology as a tool to assess the welfare impact of inherited defects on the pedigree dog population. Anim Welf. 2010;19:67–75.
Asher L, Diesel G, Summers JF, McGreevy PD, Collins LM. Inherited defects in pedigree dogs. Part 1: disorders related to breed standards. Vet J. 2009;182(3):402–11.
Summers JF, Diesel G, Asher L, McGreevy PD, Collins LM. Inherited defects in pedigree dogs. Part 2: disorders that are not related to breed standards. Vet J. 2010;183(1):39–45.
Bateson P. Independent inquiry into dog breeding. Cambridge: University of Cambridge; 2010.
VetCompass: VetCompass: Health surveillance for UK companion animals [http://www.rvc.ac.uk/VetCOMPASS/].
O'Neill DG, Church DB, McGreevy PD, Thomson PC, Brodbelt DC. Prevalence of disorders recorded in dogs attending primary-care veterinary practices in England. PLoS One. 2014;9(3):1–16.
The VeNom Coding Group: VeNom Veterinary Nomenclature [http://www.venomcoding.org].
Willard MD, Tvedten H. In: Willard MD, Tvedten H, editors. General Laboratory Concepts. 5th ed. St. Louis, Miss.: Saunders: Small Animal Clinical Diagnosis by Laboratory Methods; 2012.
Sleator DD, Endre Tarjan R. A data structure for dynamic trees. J Comput Syst Sci. 1983;26(3):362–91.
Kirkwood BR, Sterne JAC. Essential Medical Statistics. 2nd ed. Oxford: Blackwell Science; 2003.
Agresti A, Coull BA. Approximate is better than “exact” for interval estimation of binomial proportions. Am Stat. 1998;52(2):119–26.
Downes M, Canty MJ, More SJ. Demography of the pet dog and cat population on the island of Ireland and human factors influencing pet ownership. Preventive Veterinary Med. 2009;92(1–2):140–9.
Stavisky J, Brennan M, Downes M, Dean R. Demographics and economic burden of un-owned cats and dogs in the UK: results of a 2010 census. BMC Vet Res. 2012;8(1):163.
Ratsitorahina M, Rasambainarivo JH, Raharimanana S, Rakotonandrasana H, Andriamiarisoa M-P, Rakalomanana FA, et al. Dog ecology and demography in Antananarivo, 2007. BMC Vet Res. 2009;5(1):1–7.
O'Neill DG, Scudder C, Faire JM, Church DB, McGreevy PD, Thomson PC, et al. Epidemiology of hyperadrenocorticism among 210,824 dogs attending primary-care veterinary practices in the UK from 2009 to 2014. J Small Anim Pract. 2016;57(7):365–73.
Taylor-Brown FE, Meeson RL, Brodbelt DC, Church DB, McGreevy PD, Thomson PC, et al. Epidemiology of cranial cruciate ligament disease diagnosis in dogs attending primary-care veterinary practices in England. Vet Surg. 2015;44(6):777–83.
Mattin MJ, Boswood A, Church DB, López-Alvarez J, McGreevy PD, O'Neill DG, et al. Prevalence of and risk factors for degenerative mitral valve disease in dogs attending primary-care veterinary practices in England. J Vet Intern Med. 2015;29(3):847–54.
O'Neill DG, Elliott J, Church DB, McGreevy PD, Thomson PC, Brodbelt DC. Chronic kidney disease in dogs in UK veterinary practices: prevalence, risk factors, and survival. J Vet Intern Med. 2013;27(4):814–21.
O'Neill DG, Meeson RL, Sheridan A, Church DB, Brodbelt DC. The epidemiology of patellar luxation in dogs attending primary-care veterinary practices in England. Canine Genetics and Epidemiology. 2016;3(1):1–12.
Egenvall A, Nødtvedt A, Penell J, Gunnarsson L, Bonnett BN. Insurance data for research in companion animals: benefits and limitations. Acta Vet Scand. 2009;51:42.
Shore ER, Douglas DK, Riley ML. What's in it for the companion animal? Pet attachment and college students' behaviors toward pets. J Appl Anim Welf Sci. 2005;8(1):1–11.
O'Neill DG, Church DB, McGreevy PD, Thomson PC, Brodbelt DC. Longevity and mortality of owned dogs in England. Vet J. 2013;198(3):638–43.
Adams VJ, Evans KM, Sampson J, Wood JLN. Methods and mortality results of a health survey of purebred dogs in the UK. J Small Anim Pract. 2010;51(10):512–24.
Proschowsky HF, Rugbjerg H, Ersbøll AK. Mortality of purebred and mixed-breed dogs in Denmark. Preventive Veterinary Medicine. 2003;58(1–2):63–74.
Patronek GJ, Waters DJ, Glickman LT. Comparative longevity of pet dogs and humans: implications for gerontology research. Journal of Gerontology: Biological Sciences. 1997;52(3):B171–B8.
Christensen K, Johnson TE, Vaupel JW. The quest for genetic determinants of human longevity: challenges and insights. Nat Rev Genet. 2006;7(6):436–48.
D’Aquila P, Rose G, Bellizzi D, Passarino G. Epigenetics and aging. Maturitas. 2013;74(2):130–6.
Mariani F, Pérez-Barahona A, Raffin N. Life expectancy and the environment. J Econ Dyn Control. 2010;34(4):798–815.
Calboli FC, Sampson J, Fretwell N, Balding DJ. Population structure and inbreeding from pedigree analysis of purebred dogs. Genetics. 2008;179(1):593–601.
Sampson J, Binns MM. The kennel Club and the early history of dog shows and breed clubs. In: Ostrander E, editor. The dog and its genome: CSHL press; 2007. p. 19–30.
Parker HG, Shearin AL, Ostrander EA. Man’s best friend becomes biology’s best in show: genome analyses in the domestic dog. Annu Rev Genet. 2010;44:309–36.
Wayne RK, vonHoldt BM. Evolutionary genomics of dog domestication. Mamm Genome. 2012;23(1):3–18.
Boyko AR. The domestic dog: man's best friend in the genomic era. Genome Biol. 2011;12(2):216.
Lequarré A-S, Andersson L, André C, Fredholm M, Hitte C, Leeb T, et al. LUPA: a European initiative taking advantage of the canine genome architecture for unravelling complex disorders in both human and dogs. Vet J. 2011;189(2):155–9.
Lewis T, Blott S, Woolliams J. Comparative analyses of genetic trends and prospects for selection against hip and elbow dysplasia in 15 UK dog breeds. BMC Genet. 2013;14(1):16.
Collins LM, Asher L, Summers J, McGreevy P. Getting priorities straight: risk assessment and decision-making in the improvement of inherited disorders in pedigree dogs. Vet J. 2011;189(2):147–54.
Parker HG, Kim LV, Sutter NB, Carlson S, Lorentzen TD, Malek TB, et al. Genetic structure of the purebred domestic dog. Science. 2004;304(5674):1160–4.
Johns R. Our Friends the Dandie Dinmont and Skye Terriers. London: Methuen & Co. Ltd.; 1938.
Gough A, Thomas A, O'Neill D. Breed predispositions to disease in dogs and cats. 3rd ed. Wiley-Blackwell: Chichester, west Sussex; 2017.
Pfeiffer DU: Veterinary Epidemiology - An Introduction 2002.
Gorrel C. In: Nind F, editor. Small animal dentistry. 1st ed. Saunders Elsevier: Edinburgh; 2008.
Niemiec BA, editor. Veterinary periodontology. 1st ed. Ames, Iowa: John Wiley & Sons; 2013.
Horst OV, Cunha-Cruz J, Zhou L, Manning W, Mancl L, DeRouen TA. Prevalence of pain in the orofacial regions in patients visiting general dentists in the Northwest Practice-based REsearch Collaborative in Evidence-based DENTistry research network. J American Dental Assoc. 2015;146(10):721–8.e3.
Lipton J, Ship J, Larach-Robinson D. Estimated prevalence and distribution of reported orofacial pain in the United States. J Am Dent Assoc. 1993;124(10):115–21.
Acharya S, Tandon S. The effect of early childhood caries on the quality of life of children and their parents. Contemporary Clinical Dentistry. 2011;2(2):98–101.
Low W, Tan S, Schwartz S. The effect of severe caries on the quality of life in young children. Pediatr Dent. 1999;21(6):325–6.
Niemiec BA. The importance of dental radiology. European journal of companion animal. Practice. 2010;20(3):219–29.
Bartlett PC, Van Buren JW, Bartlett AD, Zhou C. Case-control study of risk factors associated with feline and canine chronic kidney disease. Veterinary Med Int. 2010;2010:1242–9.
Glickman LT. Association between chronic azotemic kidney disease and the severity of periodontal disease in dogs. Preventive Veterinary Med. 2011;99(4):193–200.
Glickman LT, Glickman NW, Moore GE, Goldstein GS, Lewis HB. Evaluation of the risk of endocarditis and other cardiovascular events on the basis of the severity of periodontal disease in dogs. J Am Vet Med Assoc. 2009;234(4):486–94.
DeBowes LJ, Mosier D, Logan E, Harvey C, Lowry S, Richardson DC. Association of periodontal disease and histologic lesions in multiple organs from 45 dogs. J Vet Dent. 1996;13(2):57–60.
O'Neill DG, Darwent EC, Church DB, Brodbelt DC. Demography and health of pugs under primary veterinary care in England. Canine Genetics Epidemiol. 2016;3(1):1–12.
Summers J, O'Neill D, Church D, Thomson P, McGreevy P, Brodbelt D. Prevalence of disorders recorded in cavalier king Charles spaniels attending primary-care veterinary practices in England. Canine Genetics Epidemiol. 2015;2(1):4.
Lund EM, Armstrong PJ, Kirk CA, Kolar LM, Klausner JS. Health status and population characteristics of dogs and cats examined at private veterinary practices in the United States. J Am Vet Med Assoc. 1999;214(9):1336–41.
Packer RA, Patterson EE, Taylor JF, Coates JR, Schnabel RD, O'Brien DP. Characterization and mode of inheritance of a paroxysmal dyskinesia in Chinook dogs. J Vet Intern Med. 2010;24(6):1305–13.
Demirkiran M, Jankovic J. Paroxysmal dyskinesias: clinical features and classification. Ann Neurol. 1995;38(4):571–9.
McGreevy PD, Thomson PC, Pride C, Fawcett A, Grassi T, Jones B. Prevalence of obesity in dogs examined by Australian veterinary practices and the risk factors involved. Vet Rec. 2005;156(22):695–702.
Lund EM, Armstrong PJ, Kirk CA, Klausner JS. Prevalence and risk factors for obesity in adult dogs from private US veterinary practices. Int J Applied Res Veterinary Med. 2006;4(2):177–86.
Robertson ID. The association of exercise, diet and other factors with owner-perceived obesity in privately owned dogs from metropolitan Perth, WA. Preventive Veterinary Med. 2003;58(1–2):75–83.
Sandøe P, Palmer C, Corr S, Astrup A, Bjørnvad CR. Canine and feline obesity: a one health perspective. Vet Rec. 2014;175(24):610–6.
Tvarijonaviciute A, Ceron JJ, Holden SL, Cuthbertson DJ, Biourge V, Morris PJ, et al. Obesity-related metabolic dysfunction in dogs: a comparison with human metabolic syndrome. BMC Vet Res. 2012;8(1):1–8.
O'Neill DG, Jackson C, Guy JH, Church DB, McGreevy PD, Thomson PC, et al. Epidemiological associations between brachycephaly and upper respiratory tract disorders in dogs attending veterinary practices in England. Canine Genetics Epidemiol. 2015;2(1):10.
German AJ, Titcomb JM, Holden SL, Queau Y, Morris PJ, Biourge V. Cohort study of the success of controlled weight loss programs for obese dogs. J Vet Intern Med. 2015;29(6):1547–55.
O'Neill D, Church D, McGreevy P, Thomson P, Brodbelt D. Approaches to canine health surveillance. Canine Genetics Epidemiol. 2014;1(1):2.
Roedler FS, Pohl S, Oechtering GU. How does severe brachycephaly affect dog’s lives? Results of a structured preoperative owner questionnaire. Vet J. 2013;198(3):606–10.
CAWC: Breeding and welfare in companion animals: welfare aspects of modifications, through selective breeding or biotechnological methods, to the form, function, or behaviour of companion animals. Sidmouth, Devon: Companion Animal Welfare Council,, 2006.
Collins R, MacMahon S. Reliable assessment of the effects of treatment on mortality and major morbidity, I: clinical trials. Lancet. 2001;357(9253):373–80.