Toxicities of docetaxel: original drug versus generics—a comparative study about 81 cases

Table 5 Comparative analysis of toxicity: original drug versus generic no. 3

	Original drug (n = 38)	Generic no. 3 (n = 11)	p
Hypersensitivity	1 (2.6 %)	0 (0 %)	1
Peripheral sensory neuropathy	2 (5.3 %)	3 (27.3 %)	0.06
Hematological toxicities	5 (13.2 %)	7 (63.6 %)	0.002
Febrile neutropenia	1 (2.6 %)	2 (18.2 %)	0.12
Gastrointestinal toxicity	2 (5.3 %)	1 (9.1 %)	0.54
Skin toxicity (extra nail hypermelanosis)	0 (0 %)	1 (9.1 %)	0.22
Treatment discontinuation	3 (7.9 %)	8 (72.7 %)	<0.001