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Table 5 Comparative analysis of toxicity: original drug versus generic no. 3

From: Toxicities of docetaxel: original drug versus generics—a comparative study about 81 cases

  Original drug
(n = 38)
Generic no. 3
(n = 11)
p
Hypersensitivity 1 (2.6 %) 0 (0 %) 1
Peripheral sensory neuropathy 2 (5.3 %) 3 (27.3 %) 0.06
Hematological toxicities 5 (13.2 %) 7 (63.6 %) 0.002
Febrile neutropenia 1 (2.6 %) 2 (18.2 %) 0.12
Gastrointestinal toxicity 2 (5.3 %) 1 (9.1 %) 0.54
Skin toxicity (extra nail hypermelanosis) 0 (0 %) 1 (9.1 %) 0.22
Treatment discontinuation 3 (7.9 %) 8 (72.7 %) <0.001
  1. Italic values indicate statistical significants