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Table 3 Comparative analysis of toxicity: original drug versus generic no. 1

From: Toxicities of docetaxel: original drug versus generics—a comparative study about 81 cases

  Original drug
(n = 38)
Generic no. 1
(n = 15)
p
Hypersensitivity 1 (2.6 %) 0 (0 %) 1
Peripheral sensory neuropathy 2 (5.3 %) 2 (13.3 %) 0.56
Hematological toxicities 5 (13.2 %) 3 (20 %) 0.67
Febrile neutropenia 1 (2.6 %) 1 (6.7 %) 0.49
Gastrointestinal toxicity 2 (5.3 %) 2 (13.3 %) 0.56
Skin toxicity (hand foot syndrome grade III) 0 (0 %) 1 (6.7 %) 0.28
Treatment discontinuation 3 (7.9 %) 4 (26.7 %) 0.09