Toxicities of docetaxel: original drug versus generics—a comparative study about 81 cases

Table 2 Comparative analysis of the toxicity of docetaxel: original drug versus generics

Toxicities	Original drug (n = 38)	Generics (n = 43)	p
Hypersensitivity	1 (2.6 %)	0 (0 %)	0.46
Peripheral sensory neuropathy	2 (5.3 %)	7 (16.3 %)	0.16
Hematological toxicities	5 (13.2 %)	14 (32.6 %)	0.04
Febrile neutropenia	1 (2.6 %)	4 (9.3 %)	0.36
Gastrointestinal toxicity	2 (5.3 %)	6 (14 %)	0.27
Skin toxicity	0 (0 %)	5 (11.6 %)	0.05
Extra nail hypermelanosis	0 (0 %)	1 (2.3 %)	1
Hand foot syndrome grade III	0 (0 %)	3 (7 %)	0.24
Ichthyosis-like eruption	0 (0 %)	1 (2.3 %)	1
Treatment discontinuation	3 (7.9 %)	17 (39.5 %)	0.001