The following collaborating authors from the Knowledge Base workgroup of the Observational Health Data Sciences and Informatics (OHDSI) collaborative participated in creating LAERTES and authoring this manuscript:
Richard D. Boyce, University of Pittsburgh, Pittsburgh, PA, email@example.com
Erica A. Voss, Janssen Research & Development, LLC, Titusville, NJ, EVoss3@its.jnj.com
Vojtech Huser, National Institutes of Health, Bethesda, MD, firstname.lastname@example.org
Lee Evans, LTS Computing LLC, West Chester, PA, email@example.com
Christian Reich, QuintilesIMS, Burlington MA, firstname.lastname@example.org
Jon D. Duke, Georgia Tech Research Institute, Atlanta, GA, Jon.Duke@gatech.edu
Nicholas P. Tatonetti, Herbert Irving Assistant Professor of Biomedical Informatics, Columbia University, New York, NY, email@example.com
Tal Lorberbaum, Columbia University, New York, NY, firstname.lastname@example.org
Michel Dumontier, Stanford University, Stanford, CA, email@example.com
Manfred Hauben, MD. MPH, Pfizer Inc, New York University Medical Center, New York, NY, firstname.lastname@example.org
Magnus Wallberg, Uppsala Monitoring Centre, Uppsala, Sweden, Magnus.Wallberg@who-umc.org
Lili Peng, AstraZeneca R&D, Boston, MA, Lili.Peng@astrazeneca.com
Sara Dempster, AstraZeneca R&D, Boston, MA, email@example.com
Yongqun He, University of Michigan Medical School, Ann Arbor, Michigan, firstname.lastname@example.org
Anthony G. Sena, Janssen Research & Development, LLC, Titusville, NJ, email@example.com
Vassilis Koutkias, Institute of Applied Biosciences, Center for Research & Technology Hellas, Thermi, Thessaloniki, Greece, firstname.lastname@example.org
Pantelis Natsiavas, Institute of Applied Biosciences, Center for Research & Technology Hellas, Thermi, Thessaloniki, Greece, email@example.com
Patrick B. Ryan, Janssen Research & Development, LLC, Titusville, NJ, firstname.lastname@example.org
This research was funded in part by the US National Institute on Aging (K01AG044433), and the National Library of Medicine (R01LM011838).
Availability of data and materials
The datasets used and/or analyzed during the current study available from the corresponding author on reasonable request. Links are provided within this published article to web services and an experimental user interface providing data from the LAERTES evidence base.
This was a collaborative project. Please see the list of collaborating authors in the Acknowledgements sections. RDB was the lead developer of LAERTES and the main author on the manuscript. Other major contributors to writing the manuscript and the design and implementation of LAERTES were EAV, VH, LE, CR, JDD, NT, MD, MW, AGS, and PR. MH made significant contributions to clarifying medication safety investigation use cases for LAERTES. LP and SD contributed to data quality assurance and drug development use cases. YH provided input on the representation of health outcomes of interest. All authors read and approved the final manuscript.
The authors have no competing interests to report. The opinions expressed are those of the authors and do not necessarily represent those of their employers.
Consent for publication
Ethics approval and consent to participate