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Table 3 CIMP status and risk of cervical lesion

From: The CpG island methylator phenotype increases the risk of high-grade squamous intraepithelial lesions and cervical cancer

  CIMP OR CI P
Negative
n
High
n
Non-SIL 16 2 1   
LSIL 43 1 0.19 0.003–3.92 0.141
HSIL 1 15 120 7.95–5342.9 0.0000
CC 1 25 200 13.75–8683.9 0.0000
Non-SIL 16 2 1   
HSIL and CC 2 40 160 16.64–1960.8 0.0000
Non-SIL and LSIL 59 3 1   
HSIL and CC 2 40 393.3 52.9–4040.78 0.0000
  Negative + low
n
High
n
   
Non-SIL 57 2 1   
LSIL 107 1 0.27 0.004–5.26 0.251
HSIL 14 15 30.5 5.77–290-09 0.0000
CC 26 25 27.4 5.91–248.19 0.0000
  1. Significant values for associations are indicated in bold
  2. CIMP, CpG island methylation phenotype; OR, odd ratio; CI, confidence interval; CC, cervical cancer; HSIL, high-grade squamous intraepithelial lesion; LSIL, low-grade squamous intraepithelial lesion; Non-SIL, negative for squamous intraepithelial lesion